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TdT 抗体 (N-Term)

DNTT 适用: 人, 小鼠, 大鼠, 马, 犬, Pig, 兔, Cow, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2784740
发货至: 中国
  • 抗原 See all TdT (DNTT) 抗体
    TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))
    抗原表位
    • 16
    • 9
    • 8
    • 8
    • 6
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 85
    • 18
    • 15
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 马, 犬, Pig, 兔, Cow, 豚鼠
    宿主
    • 73
    • 12
    克隆类型
    • 69
    • 16
    多克隆
    标记
    • 40
    • 8
    • 7
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TdT antibody is un-conjugated
    应用范围
    • 52
    • 44
    • 9
    • 9
    • 8
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    FQDLVVFILE KKMGTTRRAF LMELARRKGF RVENELSDSV THIVAENNSG
    预测反应
    Cow: 100%, Dog: 79%, Guinea Pig: 82%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against DNTT. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human DNTT
    Top Product
    Discover our top product DNTT Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 509 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))
    别名
    DNTT (DNTT 产品)
    别名
    TdT antibody, TDT antibody, BB160593 antibody, Tdt antibody, dntt-A antibody, dntt antibody, DNA nucleotidylexotransferase antibody, deoxynucleotidyltransferase, terminal antibody, DNA nucleotidylexotransferase L homeolog antibody, terminal deoxynucleotidyl transferase antibody, DNTT antibody, dntt antibody, Dntt antibody, dntt.L antibody, tdt antibody
    背景
    DNTT is a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, DNTT is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
    Alias Symbols: TDT
    Protein Interaction Partner: REL, APOA1, DNTTIP1, UBC, PRPF19, DNTTIP2, PCNA, XRCC6, ABTB2, CUL3,
    Protein Size: 509
    分子量
    58 kDa
    基因ID
    1791
    NCBI登录号
    NM_004088, NP_004079
    UniProt
    P04053
    途径
    DNA Damage Repair
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