TdT 抗体 (N-Term)
Quick Overview for TdT 抗体 (N-Term) (ABIN2784740)
抗原
See all TdT (DNTT) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- FQDLVVFILE KKMGTTRRAF LMELARRKGF RVENELSDSV THIVAENNSG
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预测反应
- Cow: 100%, Dog: 79%, Guinea Pig: 82%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against DNTT. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human DNTT
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anti-Deoxynucleotidyltransferase, terminal (DNTT) (AA 52-192) antibody
DNTT 适用: 人, 大鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 4B10A6 unconjugated
anti-Deoxynucleotidyltransferase, terminal (DNTT) (AA 52-192) antibodyDNTT 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4B10C3 unconjugated
anti-Deoxynucleotidyltransferase, terminal (DNTT) (AA 1-110) antibodyDNTT 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H5 unconjugated
anti-Deoxynucleotidyltransferase, terminal (DNTT) antibodyDNTT 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-453R unconjugated Recombinant Antibody
anti-Deoxynucleotidyltransferase, terminal (DNTT) (AA 351-450) antibodyDNTT 适用: 人, 小鼠, 大鼠 ELISA, FACS, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Deoxynucleotidyltransferase, terminal (DNTT) (AA 1-509) antibodyDNTT 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Deoxynucleotidyltransferase, terminal (DNTT) (Internal Region) antibodyDNTT 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Deoxynucleotidyltransferase, terminal (DNTT) (AA 316-509) antibodyDNTT 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Deoxynucleotidyltransferase, terminal (DNTT) (AA 32-81) antibodyDNTT 适用: 人, 小鼠, 大鼠, 马, Cow, 犬, Pig, 兔, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Deoxynucleotidyltransferase, terminal (DNTT) antibodyDNTT 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 509 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))
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别名
- DNTT
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背景
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DNTT is a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, DNTT is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
Alias Symbols: TDT
Protein Interaction Partner: REL, APOA1, DNTTIP1, UBC, PRPF19, DNTTIP2, PCNA, XRCC6, ABTB2, CUL3,
Protein Size: 509 -
分子量
- 58 kDa
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基因ID
- 1791
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NCBI登录号
- NM_004088, NP_004079
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UniProt
- P04053
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途径
- DNA Damage Repair
抗原
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