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COPA 抗体 (N-Term)

There are 2+ publications for this product available. The 兔多克隆 anti-COPA antibody is suitable to detect COPA in samples from 人, 小鼠, 大鼠, 犬, 斑马鱼, 马, 豚鼠, 兔, Cow, 山羊和 Saccharomyces cerevisiae. It has been validated for WB.

1 image

(2 references)

产品编号 ABIN2784677

发货至: 中国

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Quick Overview for COPA 抗体 (N-Term) (ABIN2784677)

抗原

See all COPA 抗体

COPA (Coatomer Protein Complex, Subunit alpha (COPA))

适用

人, 小鼠, 大鼠, 犬, 斑马鱼, 马, 豚鼠, 兔, Cow, 山羊, Saccharomyces cerevisiae

宿主

兔

克隆类型

多克隆

标记

This COPA antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product COPA Primary Antibody

抗原表位
1

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1

1

1

1

1

1
N-Term

原理

COPA Antibody - N-terminal region

序列

PWILTSLHNG VIQLWDYRMC TLIDKFDEHD GPVRGIDFHK QQPLFVSGGD

预测反应

Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 100%

产品特性

This is a rabbit polyclonal antibody against COPA. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human COPA
anti-Coatomer Protein Complex, Subunit alpha (COPA) antibody
COPA 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated

anti-Coatomer Protein Complex, Subunit alpha (COPA) (AA 1174-1224) antibody
COPA 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated

anti-Coatomer Protein Complex, Subunit alpha (COPA) (AA 1-19) antibody
COPA 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, 马, Cow, Bat, 小鸡, Hamster, 猴, Pig, 非洲爪蟾 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Coatomer Protein Complex, Subunit alpha (COPA) (Internal Region) antibody
Verified COPA 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Coatomer Protein Complex, Subunit alpha (COPA) (AA 22-71) antibody
COPA 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, 马, 豚鼠, 兔, Cow, Bat, 小鸡, Hamster, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated

anti-Coatomer Protein Complex, Subunit alpha (COPA) (AA 396-445) antibody
COPA 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, 马, 豚鼠, 兔, Bat, 小鸡, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated

anti-Coatomer Protein Complex, Subunit alpha (COPA) (AA 550-650) antibody
COPA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Coatomer Protein Complex, Subunit alpha (COPA) antibody
COPA 适用: 人 WB 宿主: 兔 Monoclonal 23GB3485 unconjugated Recombinant Antibody

anti-Coatomer Protein Complex, Subunit alpha (COPA) (N-Term) antibody
COPA 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated

anti-Coatomer Protein Complex, Subunit alpha (COPA) (AA 3-100) antibody
COPA 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

说明

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51893-100UG

限制

仅限研究用
状态

Liquid

浓度

0.5 mg/mL

缓冲液

Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

prevent freeze-thaw cycles

储存条件

4 °C,-20 °C

储存方法

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Li, Custer, Gilson, Hao, Beattie, Androphy: "α-COP binding to the survival motor neuron protein SMN is required for neuronal process outgrowth." in: Human molecular genetics, Vol. 24, Issue 25, pp. 7295-307, (2015) (PubMed).

Ting, Wen, Liu, Hsieh-Li, Li, Lin-Chao: "The spinal muscular atrophy disease protein SMN is linked to the Golgi network." in: PLoS ONE, Vol. 7, Issue 12, pp. e51826, (2013) (PubMed).
抗原

COPA (Coatomer Protein Complex, Subunit alpha (COPA))

别名

COPA

背景

Targeted Subunit: alpha
Background Information: In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone.In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms.
Gene Name: Coatomer protein complex, subunit alpha
Alternative Symbols: AILJK, HEP-COP, alpha-COP
Protein Name: Coatomer subunit alpha

分子量

138 kDa

基因ID

1314

NCBI登录号

NP_004362

UniProt

P53621

途径

Hormone Activity