COPA 抗体 (N-Term)
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北京 101111
Quick Overview for COPA 抗体 (N-Term) (ABIN2784677)
抗原
See all COPA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- PWILTSLHNG VIQLWDYRMC TLIDKFDEHD GPVRGIDFHK QQPLFVSGGD
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预测反应
- Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against COPA. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human COPA
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anti-Coatomer Protein Complex, Subunit alpha (COPA) antibody
COPA 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Coatomer Protein Complex, Subunit alpha (COPA) (AA 1-19) antibodyCOPA 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, 马, Cow, Bat, 小鸡, Hamster, 猴, Pig, 非洲爪蟾 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Coatomer Protein Complex, Subunit alpha (COPA) (AA 550-650) antibodyCOPA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Coatomer Protein Complex, Subunit alpha (COPA) antibodyCOPA 适用: 人 WB 宿主: 兔 Monoclonal 23GB3485 unconjugated Recombinant Antibody
anti-Coatomer Protein Complex, Subunit alpha (COPA) (Internal Region) antibodyVerified COPA 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Coatomer Protein Complex, Subunit alpha (COPA) (AA 3-100) antibodyCOPA 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Coatomer Protein Complex, Subunit alpha (COPA) (AA 396-445) antibodyCOPA 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, 马, 豚鼠, 兔, Bat, 小鸡, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Coatomer Protein Complex, Subunit alpha (COPA) (AA 22-71) antibodyCOPA 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, 马, 豚鼠, 兔, Cow, Bat, 小鸡, Hamster, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Coatomer Protein Complex, Subunit alpha (COPA) (N-Term) antibodyCOPA 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1224 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "α-COP binding to the survival motor neuron protein SMN is required for neuronal process outgrowth." in: Human molecular genetics, Vol. 24, Issue 25, pp. 7295-307, (2015) (PubMed).
: "The spinal muscular atrophy disease protein SMN is linked to the Golgi network." in: PLoS ONE, Vol. 7, Issue 12, pp. e51826, (2013) (PubMed).
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: "α-COP binding to the survival motor neuron protein SMN is required for neuronal process outgrowth." in: Human molecular genetics, Vol. 24, Issue 25, pp. 7295-307, (2015) (PubMed).
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- COPA (Coatomer Protein Complex, Subunit alpha (COPA))
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别名
- COPA
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背景
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In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone.In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms.
Alias Symbols: FLJ26320, HEP-COP
Protein Interaction Partner: UBC, SUMO2, SMN1, STAU1, NUDCD1, SUMO1, NEDD8, RPA3, RPA2, RPA1, SUZ12, RNF2, COPZ1, DHX38, COPB2, CCT3, TCP1, SEPT2, ARCN1, UBD, VCAM1, ITGA4, COPB1, COPG2, COPG1, COPE, SEPT9, SEC23A, SEC24C, UBXN6, FBXO6, LMAN1, SACM1L, DDX20, TMED10, GEMIN2, COPA, CDK
Protein Size: 1224 -
分子量
- 135 kDa
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基因ID
- 1314
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NCBI登录号
- NM_004371, NP_004362
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UniProt
- P53621
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途径
- Hormone Activity
抗原
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