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COPA 抗体 (N-Term)

Name: COPA 抗体 (N-Term)
SKU: ABIN2784677
Availability: OutOfStock

This anti-COPA antibody is a 兔多克隆 antibody detecting COPA in WB. Suitable for 人, 小鼠, 大鼠, 犬, 斑马鱼, 马, 豚鼠, 兔, Cow, 山羊和 Saccharomyces cerevisiae. This Primary Antibody has been cited in 2+ publications.

WB Suggested Anti-COPA Antibody Titration: 0. (COPA 抗体 (N-Term))

1 image

(2 references)

产品编号 ABIN2784677

发货至: 中国

Quick Overview for COPA 抗体 (N-Term) (ABIN2784677)

抗原

See all COPA 抗体

COPA (Coatomer Protein Complex, Subunit alpha (COPA))

适用

人, 小鼠, 大鼠, 犬, 斑马鱼, 马, 豚鼠, 兔, Cow, 山羊, Saccharomyces cerevisiae

宿主

兔

克隆类型

多克隆

标记

This COPA antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product COPA Primary Antibody

抗原表位
1

1

1

1

1

1

1

1
N-Term

序列

PWILTSLHNG VIQLWDYRMC TLIDKFDEHD GPVRGIDFHK QQPLFVSGGD

预测反应

Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 100%

产品特性

This is a rabbit polyclonal antibody against COPA. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human COPA
anti-Coatomer Protein Complex, Subunit alpha (COPA) antibody
COPA 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated

anti-Coatomer Protein Complex, Subunit alpha (COPA) (AA 1-19) antibody
COPA 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, 马, Cow, Bat, 小鸡, Hamster, 猴, Pig, 非洲爪蟾 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Coatomer Protein Complex, Subunit alpha (COPA) (AA 3-100) antibody
COPA 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Coatomer Protein Complex, Subunit alpha (COPA) (Internal Region) antibody
Verified COPA 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Coatomer Protein Complex, Subunit alpha (COPA) (AA 22-71) antibody
COPA 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, 马, 豚鼠, 兔, Cow, Bat, 小鸡, Hamster, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated

anti-Coatomer Protein Complex, Subunit alpha (COPA) (AA 396-445) antibody
COPA 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, 马, 豚鼠, 兔, Bat, 小鸡, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated

anti-Coatomer Protein Complex, Subunit alpha (COPA) (AA 550-650) antibody
COPA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Coatomer Protein Complex, Subunit alpha (COPA) (N-Term) antibody
COPA 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated

anti-Coatomer Protein Complex, Subunit alpha (COPA) (AA 1174-1224) antibody
COPA 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated

anti-Coatomer Protein Complex, Subunit alpha (COPA) antibody
COPA 适用: 人, 小鼠, 大鼠 ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 1224 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Li, Custer, Gilson, Hao, Beattie, Androphy: "α-COP binding to the survival motor neuron protein SMN is required for neuronal process outgrowth." in: Human molecular genetics, Vol. 24, Issue 25, pp. 7295-307, (2015) (PubMed).

Ting, Wen, Liu, Hsieh-Li, Li, Lin-Chao: "The spinal muscular atrophy disease protein SMN is linked to the Golgi network." in: PLoS ONE, Vol. 7, Issue 12, pp. e51826, (2013) (PubMed).
抗原

COPA (Coatomer Protein Complex, Subunit alpha (COPA))

别名

COPA

背景

In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone.In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms.
Alias Symbols: FLJ26320, HEP-COP
Protein Interaction Partner: UBC, SUMO2, SMN1, STAU1, NUDCD1, SUMO1, NEDD8, RPA3, RPA2, RPA1, SUZ12, RNF2, COPZ1, DHX38, COPB2, CCT3, TCP1, SEPT2, ARCN1, UBD, VCAM1, ITGA4, COPB1, COPG2, COPG1, COPE, SEPT9, SEC23A, SEC24C, UBXN6, FBXO6, LMAN1, SACM1L, DDX20, TMED10, GEMIN2, COPA, CDK
Protein Size: 1224

分子量

135 kDa

基因ID

1314

NCBI登录号

NM_004371, NP_004362

UniProt

P53621

途径

Hormone Activity