CHN2 抗体 (N-Term)
Quick Overview for CHN2 抗体 (N-Term) (ABIN2784666)
抗原
See all CHN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- NHFNYEKTHN FKVHTFRGPH WCEYCANFMW GLIAQGVRCS DCGLNVHKQC
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against CHN2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CHN2
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anti-Chimerin (Chimaerin) 2 (CHN2) (AA 101-323) antibody
CHN2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chimerin (Chimaerin) 2 (CHN2) (AA 101-280) antibodyCHN2 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chimerin (Chimaerin) 2 (CHN2) (AA 1-91) antibodyCHN2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chimerin (Chimaerin) 2 (CHN2) (C-Term) antibodyVerified CHN2 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Chimerin (Chimaerin) 2 (CHN2) (AA 33-82) antibodyCHN2 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Chimerin (Chimaerin) 2 (CHN2) (AA 71-120) antibodyCHN2 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, 豚鼠, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Chimerin (Chimaerin) 2 (CHN2) (AA 1-264) antibodyCHN2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chimerin (Chimaerin) 2 (CHN2) (AA 162-192), (Middle Region) antibodyCHN2 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 332 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CHN2 (Chimerin (Chimaerin) 2 (CHN2))
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别名
- CHN2
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背景
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CHN2 is a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. This protein has GTPase-activating protein activity that is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. CHN2 plays a role in the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors, and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men. This gene is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. This protein has GTPase-activating protein activity that is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. The protein plays a role in the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors, and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: ARHGAP3, BCH, MGC138360, RHOGAP3, CHN2-3
Protein Interaction Partner: ERBB3, RAC1, RACGAP1, TGFBR1, BAG6, AKT1,
Protein Size: 332 -
分子量
- 38 kDa
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基因ID
- 1124
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NCBI登录号
- NM_001039936, NP_001035025
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UniProt
- P52757
抗原
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