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CHN2 抗体 (N-Term)

This anti-CHN2 antibody is a 兔 多克隆 antibody detecting CHN2 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 马, 兔, 犬, 豚鼠 和 斑马鱼.
产品编号 ABIN2784666
发货至: 中国

Quick Overview for CHN2 抗体 (N-Term) (ABIN2784666)

抗原

See all CHN2 抗体
CHN2 (Chimerin (Chimaerin) 2 (CHN2))

适用

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人, 小鼠, 大鼠, Cow, 马, 兔, 犬, 豚鼠, 斑马鱼

宿主

  • 26
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克隆类型

  • 27
多克隆

标记

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This CHN2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    NHFNYEKTHN FKVHTFRGPH WCEYCANFMW GLIAQGVRCS DCGLNVHKQC

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

    产品特性

    This is a rabbit polyclonal antibody against CHN2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human CHN2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 332 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    CHN2 (Chimerin (Chimaerin) 2 (CHN2))

    别名

    CHN2

    背景

    CHN2 is a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. This protein has GTPase-activating protein activity that is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. CHN2 plays a role in the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors, and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men. This gene is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. This protein has GTPase-activating protein activity that is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. The protein plays a role in the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors, and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
    Alias Symbols: ARHGAP3, BCH, MGC138360, RHOGAP3, CHN2-3
    Protein Interaction Partner: ERBB3, RAC1, RACGAP1, TGFBR1, BAG6, AKT1,
    Protein Size: 332

    分子量

    38 kDa

    基因ID

    1124

    NCBI登录号

    NM_001039936, NP_001035025

    UniProt

    P52757
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