ABAT 抗体 (Middle Region)
Quick Overview for ABAT 抗体 (Middle Region) (ABIN2784615)
抗原
See all ABAT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- IIVEPIQSEG GDNHASDDFF RKLRDIARKH GCAFLVDEVQ TGGGCTGKFW
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预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against ABAT. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ABAT
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anti-4-Aminobutyrate Aminotransferase (ABAT) (AA 236-500) antibody
ABAT 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) (AA 29-300) antibodyABAT 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) antibodyABAT 适用: 人 WB, IHC (p), IF, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) (AA 151-250) antibodyABAT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) (AA 29-300) antibodyABAT 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) (AA 1-500) antibodyABAT 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) (C-Term) antibodyABAT 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) (Internal Region) antibodyABAT 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) (AA 249-500) antibodyABAT 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) antibodyABAT 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 500 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ABAT (4-Aminobutyrate Aminotransferase (ABAT))
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别名
- ABAT
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背景
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4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities.4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95 % similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
Alias Symbols: GABA-AT, GABAT, NPD009
Protein Interaction Partner: LGR4, BAG3, ALDH5A1, ABAT,
Protein Size: 500 -
分子量
- 55 kDa
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基因ID
- 18
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NCBI登录号
- NM_020686, NP_065737
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UniProt
- P80404
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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