PAXIP1 抗体 (N-Term)
-
- 抗原 See all PAXIP1 抗体
- PAXIP1 (PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1))
-
抗原表位
- N-Term
-
适用
- 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 豚鼠, 马, 兔
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This PAXIP1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- MFDDSSDSSP EKQERNLNWT PAEVPQLAAA KRRLPQGKEP GLINLCANVP
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
- 产品特性
- This is a rabbit polyclonal antibody against PAXIP1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PAXIP1
- Top Product
- Discover our top product PAXIP1 Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 697 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- PAXIP1 (PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1))
- 别名
- PAXIP1 (PAXIP1 产品)
- 背景
-
PAXIP1 functions as a key component of the DNA damage response, and phosphoserine or phosphothreonine-specific binding modules. PAXIP1 recognizes substrates phosphorylated by the kinases ataxia telangiectasia-mutated (ATM), ataxia telangiectasia and RAD3-related (ATR) in response to gamma irradiation. It may play a role in PAX2-dependent transcriptional regulation. PAXIP1 plays a role in early development, most probably in cell proliferation.
Alias Symbols: PTIP, TNRC2, CAGF28, CAGF29, PACIP1, PAXIP1L, FLJ41049
Protein Interaction Partner: MAPRE2, POM121, NXT1, PPARG, XAGE1E, SMAD2, SPATA18, COMTD1, BTBD16, DIS3L, LACTB, HNRNPLL, ZNF251, ZNF622, BTBD6, C7orf50, FAM175A, TMEM120A, FAHD1, TM2D3, ATHL1, CENPU, DYNC2H1, BRCC3, KRI1, ANAPC1, NOM1, POLR1E, NCAPG, AASDHPPT, RBM25, CATSPERG, WDR48,
Protein Size: 697 - 分子量
- 74 kDa
- 基因ID
- 22976
- NCBI登录号
- NM_007349
- UniProt
- Q6ZW49
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
-