PAXIP1 抗体 (N-Term)
Quick Overview for PAXIP1 抗体 (N-Term) (ABIN2784556)
抗原
See all PAXIP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MFDDSSDSSP EKQERNLNWT PAEVPQLAAA KRRLPQGKEP GLINLCANVP
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against PAXIP1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PAXIP1
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anti-PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1) (AA 868-975) antibody
PAXIP1 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 4C11 unconjugated
anti-PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1) (AA 613-812) antibodyPAXIP1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1) (AA 1-757) antibodyPAXIP1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1) (AA 2-35), (N-Term) antibodyPAXIP1 适用: 人 WB 宿主: 兔 Polyclonal RB47860 unconjugated
anti-PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1) (AA 868-975) antibodyPAXIP1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1) (AA 248-297) antibodyPAXIP1 适用: 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 豚鼠, 马, 兔, 非洲爪蟾, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1) (N-Term) antibodyPAXIP1 适用: 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 697 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PAXIP1 (PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1))
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别名
- PAXIP1
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背景
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PAXIP1 functions as a key component of the DNA damage response, and phosphoserine or phosphothreonine-specific binding modules. PAXIP1 recognizes substrates phosphorylated by the kinases ataxia telangiectasia-mutated (ATM), ataxia telangiectasia and RAD3-related (ATR) in response to gamma irradiation. It may play a role in PAX2-dependent transcriptional regulation. PAXIP1 plays a role in early development, most probably in cell proliferation.
Alias Symbols: PTIP, TNRC2, CAGF28, CAGF29, PACIP1, PAXIP1L, FLJ41049
Protein Interaction Partner: MAPRE2, POM121, NXT1, PPARG, XAGE1E, SMAD2, SPATA18, COMTD1, BTBD16, DIS3L, LACTB, HNRNPLL, ZNF251, ZNF622, BTBD6, C7orf50, FAM175A, TMEM120A, FAHD1, TM2D3, ATHL1, CENPU, DYNC2H1, BRCC3, KRI1, ANAPC1, NOM1, POLR1E, NCAPG, AASDHPPT, RBM25, CATSPERG, WDR48,
Protein Size: 697 -
分子量
- 74 kDa
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基因ID
- 22976
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NCBI登录号
- NM_007349
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UniProt
- Q6ZW49
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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