HIST2H2AC 抗体 (Middle Region)
Quick Overview for HIST2H2AC 抗体 (Middle Region) (ABIN2784540)
抗原
See all HIST2H2AC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- IPRHLQLAIR NDEELNKLLG KVTIAQGGVL PNIQAVLLPK KTESHKAKSK
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against HIST2H2AC. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human HIST2H2AC
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 129 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- HIST2H2AC (Histone Cluster 2, H2ac (HIST2H2AC))
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别名
- HIST2H2AC
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背景
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. HIST2H2AC is a member of the histone H2A family.Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: H2A, H2A-GL101, H2A/q, H2AFQ, MGC74460
Protein Interaction Partner: BAP1, UBC, RNF2, INO80, UIMC1, RAD6, HDAC2, USP16, AURKB, NEDD8, CUL4A, USP15, SART3, HIST2H2BE, POLR2C, RNF168, HCVgp1, PRAME, RNF8, CRP, CENPA, HIST1H3B, EP300, KAT2A, BRCA1, BARD1, RBBP7, RBBP4, HAT1, ATXN7L3, USP22, MECP2, CHFR, DDB2, HIST1H4A, HIST1H
Protein Size: 129 -
分子量
- 14 kDa
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基因ID
- 8338
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NCBI登录号
- NM_003517, NP_003508
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UniProt
- Q16777
抗原
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