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HIST2H2AC 抗体 (AA 18-46)

HIST2H2AC 适用: 人 WB 宿主: 兔 Polyclonal RB41799 unconjugated
产品编号 ABIN1881417
发货至: 中国
  • 抗原 See all HIST2H2AC 抗体
    HIST2H2AC (Histone Cluster 2, H2ac (HIST2H2AC))
    抗原表位
    • 6
    • 5
    • 4
    • 1
    AA 18-46
    适用
    • 20
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 20
    克隆类型
    • 20
    多克隆
    标记
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    This HIST2H2AC antibody is un-conjugated
    应用范围
    • 15
    • 13
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    Rat, B, X, M, C, Pr, Zf, D
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This HIST2H2AC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the Central region of human HIST2H2AC.
    克隆位点
    RB41799
    亚型
    Ig Fraction
    Top Product
    Discover our top product HIST2H2AC Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Ishibashi, Dryhurst, Rose, Shabanowitz, Hunt, Ausió: "Acetylation of vertebrate H2A.Z and its effect on the structure of the nucleosome." in: Biochemistry, Vol. 48, Issue 22, pp. 5007-17, (2009) (PubMed).

    Karaczyn, Cheng, Buzard, Hartley, Esposito, Kasprzak: "Truncation of histone H2A's C-terminal tail, as is typical for Ni(II)-assisted specific peptide bond hydrolysis, has gene expression altering effects." in: Annals of clinical and laboratory science, Vol. 39, Issue 3, pp. 251-62, (2009) (PubMed).

    Zhao, Lang, Ito, Bonnet, Metzger, Sawatsubashi, Suzuki, Le Guezennec, Stunnenberg, Krasnov, Georgieva, Schüle, Takeyama, Kato, Tora, Devys: "A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing." in: Molecular cell, Vol. 29, Issue 1, pp. 92-101, (2008) (PubMed).

  • 抗原
    HIST2H2AC (Histone Cluster 2, H2ac (HIST2H2AC))
    别名
    HIST2H2AC (HIST2H2AC 产品)
    别名
    HIST2H2AC antibody, H2A antibody, H2A-GL101 antibody, H2A/q antibody, H2AFQ antibody, H2a-613b antibody, RGD1560965 antibody, histone cluster 1, H2A, IV antibody, histone cluster 2 H2A family member c antibody, histone cluster 2, H2ac antibody, HIST1H2A4 antibody, HIST2H2AC antibody, Hist2h2ac antibody
    背景
    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family.
    分子量
    13988
    NCBI登录号
    NP_003508
    UniProt
    Q16777
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