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CDC45 抗体 (C-Term)

CDC45 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2784521
发货至: 中国
  • 抗原 See all CDC45 抗体
    CDC45 (Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))
    抗原表位
    • 15
    • 7
    • 7
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔
    宿主
    • 60
    • 7
    克隆类型
    • 53
    • 14
    多克隆
    标记
    • 29
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDC45 antibody is un-conjugated
    应用范围
    • 36
    • 26
    • 18
    • 15
    • 13
    • 13
    • 10
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    VTVVGIPPET DSSDRKNFFG RAFEKAAEST SSRMLHNHFD LSVIELKAED
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against CDC45L. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human CDC45L
    Top Product
    Discover our top product CDC45 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 566 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    CDC45 (Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))
    别名
    CDC45L (CDC45 产品)
    别名
    cdc45l antibody, cdc45l2 antibody, porc-pi-1 antibody, CDC45L antibody, CDC45L2 antibody, PORC-PI-1 antibody, Cdc45l antibody, cell division cycle 45 antibody, cell division cycle 45 S homeolog antibody, cell division cycle 45 L homeolog antibody, cdc45 antibody, CDC45 antibody, cdc45.S antibody, Cdc45 antibody, cdc45.L antibody
    背景
    CDC45L was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple polyadenlyation sites of this gene are reported. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: CDC45, CDC45L2, PORC-PI-1, CDC45L
    Protein Interaction Partner: CEP55, UBC, FBXO6, DTD1, TOPBP1, CAMK1G, MCM10, TRAPPC3, ORC3, ORC5, CDKN2A, CDKN1A, ALB, MRE11A, CUL3, NEDD8, CDK2, L3MBTL1, HIST1H3A, CCL2, MCM7, MCM4, MCM3, ORC2, POLA1, CDK4, ORC6, ORC1, MCM6,
    Protein Size: 566
    分子量
    65 kDa
    基因ID
    8318
    NCBI登录号
    NM_003504, NP_003495
    UniProt
    O75419
    途径
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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