CDC45 抗体 (C-Term)
Quick Overview for CDC45 抗体 (C-Term) (ABIN2784521)
抗原
See all CDC45 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
序列
- VTVVGIPPET DSSDRKNFFG RAFEKAAEST SSRMLHNHFD LSVIELKAED
-
预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
-
产品特性
- This is a rabbit polyclonal antibody against CDC45L. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human CDC45L
-
-
anti-Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45) (AA 1-270) antibody
CDC45 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45) (AA 1-566) antibodyCDC45 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3F11-1F3 unconjugated
anti-Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45) (AA 1-566) antibodyCDC45 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45) (AA 477-566) antibodyCDC45 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C2 unconjugated
anti-Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45) (AA 1-566) antibodyCDC45 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45) (AA 1-566) antibodyCDC45 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45) (C-Term) antibodyCDC45 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45) (Center) antibodyCDC45 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45) (AA 236-263) antibodyCDC45 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23958 unconjugated
anti-Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45) (AA 485-566) antibodyCDC45 适用: 小鼠, 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 566 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- CDC45 (Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))
-
别名
- CDC45L
-
背景
-
CDC45L was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple polyadenlyation sites of this gene are reported. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CDC45, CDC45L2, PORC-PI-1, CDC45L
Protein Interaction Partner: CEP55, UBC, FBXO6, DTD1, TOPBP1, CAMK1G, MCM10, TRAPPC3, ORC3, ORC5, CDKN2A, CDKN1A, ALB, MRE11A, CUL3, NEDD8, CDK2, L3MBTL1, HIST1H3A, CCL2, MCM7, MCM4, MCM3, ORC2, POLA1, CDK4, ORC6, ORC1, MCM6,
Protein Size: 566 -
分子量
- 65 kDa
-
基因ID
- 8318
-
NCBI登录号
- NM_003504, NP_003495
-
UniProt
- O75419
-
途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
抗原
-
