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TNNT3 抗体 (N-Term)

Cited in 2+ publications. The 兔 多克隆 anti-TNNT3 antibody (ABIN2784497) specifically detects TNNT3 in WB. The antibody is reactive with 人, 小鼠, 大鼠, 豚鼠, 兔, Cow, 马, 犬, 山羊 和 斑马鱼 samples.
产品编号 ABIN2784497
发货至: 中国
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Quick Overview for TNNT3 抗体 (N-Term) (ABIN2784497)

抗原

See all TNNT3 抗体
TNNT3 (Fast Skeletal Troponin T (TNNT3))

适用

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人, 小鼠, 大鼠, 豚鼠, 兔, Cow, 马, 犬, 山羊, 斑马鱼

宿主

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兔

克隆类型

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多克隆

标记

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This TNNT3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    原理

    TNNT3 Antibody - N-terminal region

    序列

    PRPKLTAPKI PEGEKVDFDD IQKKRQNKDL MELQALIDSH FEARKKEEEE

    预测反应

    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against TNNT3. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human TNNT3
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51287-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • Zhang, Pereyra, Wang, Birbrair, Reisz, Files, Purcell, Feng, Messi, Feng, Chalovich, Jin, Furdui, Delbono: "Calpain inhibition rescues troponin T3 fragmentation, increases Cav1.1, and enhances skeletal muscle force in aging sedentary mice." in: Aging cell, Vol. 15, Issue 3, pp. 488-98, (2016) (PubMed).

    Zhang, Birbrair, Delbono: "Nonmyofilament-associated troponin T3 nuclear and nucleolar localization sequence and leucine zipper domain mediate muscle cell apoptosis." in: Cytoskeleton (Hoboken, N.J.), Vol. 70, Issue 3, pp. 134-47, (2013) (PubMed).

  • 抗原

    TNNT3 (Fast Skeletal Troponin T (TNNT3))

    别名

    TNNT3

    背景

    Background Information: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

    Gene Name: Troponin T type 3 (skeletal, fast)

    Alternative Symbols: TNTF, DA2B2, beta-TnTF

    Protein Name: Troponin T, fast skeletal muscle

    分子量

    32 kDa

    基因ID

    7140

    NCBI登录号

    NP_001036245

    UniProt

    P45378
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