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PARK7/DJ1 抗体 (C-Term)

This 兔 多克隆 anti-PARK7/DJ1 antibody specifically detects PARK7/DJ1 in WB 和 IHC. The antibody is reactive with 人, 小鼠, 大鼠, Cow, Pig, 犬, 马, 豚鼠 和 兔 samples.
产品编号 ABIN2784491
发货至: 中国
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Quick Overview for PARK7/DJ1 抗体 (C-Term) (ABIN2784491)

抗原

See all PARK7/DJ1 (PARK7) 抗体
PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))

适用

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人, 小鼠, 大鼠, Cow, Pig, 犬, 马, 豚鼠, 兔

宿主

  • 127
  • 19
  • 2
  • 1

克隆类型

  • 103
  • 46
多克隆

标记

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This PARK7/DJ1 antibody is un-conjugated

应用范围

  • 123
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  • 5
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    序列

    TYSENRVEKD GLILTSRGPG TSFEFALAIV EALNGKEVAA QVKAPLVLKD

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against PARK7. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human PARK7
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 189 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))

    别名

    PARK7

    背景

    PARK7 belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7.The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.
    Alias Symbols: DJ-1, DJ1, FLJ27376
    Protein Interaction Partner: GOPC, VHL, UBC, PARK7, NPM1, BBS1, SNCA, Bax, HIPK1, TDP2, PRDX5, PPARGC1A, FADD, PRDX2, TALDO1, SREBF2, SFPQ, PTEN, NONO, MAP3K5, HSPA4, CASP8, BAG1, ATP5J, AR, PINK1, TP53, SLC18A2, PARK2, NDUFS3, NDUFA4, ND1, MAP1B, CSN1S1, SUMO1, UBE2I, DAXX, UBA2, BC
    Protein Size: 189

    分子量

    20 kDa

    基因ID

    11315

    NCBI登录号

    NM_007262, NP_009193

    UniProt

    Q99497

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport
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