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DCLRE1C 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects DCLRE1C in WB. It exhibits reactivity toward 人, 小鼠, 大鼠, 豚鼠, 马, Cow, 兔, 犬 和 斑马鱼.
产品编号 ABIN2784440
发货至: 中国
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Quick Overview for DCLRE1C 抗体 (N-Term) (ABIN2784440)

抗原

See all DCLRE1C 抗体
DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))

适用

  • 70
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  • 25
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  • 1
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人, 小鼠, 大鼠, 豚鼠, 马, Cow, 兔, 犬, 斑马鱼

宿主

  • 68
  • 3
兔

克隆类型

  • 71
多克隆

标记

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This DCLRE1C antibody is un-conjugated

应用范围

  • 49
  • 25
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  • 13
  • 13
  • 8
  • 7
  • 7
  • 3
  • 2
  • 1
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Western Blotting (WB)
  • 抗原表位

    • 15
    • 12
    • 8
    • 6
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    N-Term

    原理

    DCLRE1C Antibody - N-terminal region

    序列

    SSFEGQMAEY PTISIDRFDR ENLRARAYFL SHCHKDHMKG LRAPTLKRRL

    预测反应

    Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

    产品特性

    This is a rabbit polyclonal antibody against DCLRE1C. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human DCLRE1C
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51164-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))

    别名

    DCLRE1C

    背景

    Background Information: DCLRE1C is a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity, it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA).This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity, it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA).

    Gene Name: DNA cross-link repair 1C

    Alternative Symbols: SCIDA, SNM1C, A-SCID, RS-SCID, DCLREC1C

    Protein Name: Protein artemis

    分子量

    78kDa

    基因ID

    64421

    NCBI登录号

    NP_001029027

    UniProt

    Q96SD1

    途径

    DNA Damage Repair
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