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DCLRE1C 抗体 (N-Term)

DCLRE1C 适用: 人, 小鼠, 大鼠, 豚鼠, 马, Cow, 兔, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2784440
发货至: 中国
  • 抗原 See all DCLRE1C 抗体
    DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))
    抗原表位
    • 15
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    N-Term
    适用
    • 43
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    人, 小鼠, 大鼠, 豚鼠, 马, Cow, 兔, 犬, 斑马鱼
    宿主
    • 58
    • 1
    克隆类型
    • 59
    多克隆
    标记
    • 28
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    This DCLRE1C antibody is un-conjugated
    应用范围
    • 45
    • 28
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    • 13
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    • 8
    • 5
    • 3
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    Western Blotting (WB)
    序列
    SSFEGQMAEY PTISIDRFDR ENLRARAYFL SHCHKDHMKG LRAPTLKRRL
    预测反应
    Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
    产品特性
    This is a rabbit polyclonal antibody against DCLRE1C. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human DCLRE1C
    Top Product
    Discover our top product DCLRE1C Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 692 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))
    别名
    DCLRE1C (DCLRE1C 产品)
    别名
    artemis antibody, A-SCID antibody, DCLREC1C antibody, RS-SCID antibody, SCIDA antibody, SNM1C antibody, hSNM1C antibody, Snm1l antibody, nuclease antibody, 9930121L06Rik antibody, AI661365 antibody, Art antibody, DNA cross-link repair 1C antibody, DCLRE1C antibody, Dclre1c antibody
    背景
    DCLRE1C is a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity, it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA).This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity, it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA).
    Alias Symbols: A-SCID, DCLREC1C, FLJ11360, FLJ36438, RS-SCID, SCIDA, SNM1C, hSNM1C
    Protein Interaction Partner: XRCC5, PRKDC, RAD50, NBN, MRE11A, BRCA1, ATR, ATM, PSMD9, DDB2, DDB1, FBXW7, TP53BP1,
    Protein Size: 692
    分子量
    78 kDa
    基因ID
    64421
    NCBI登录号
    NM_001033855, NP_001029027
    UniProt
    Q96SD1
    途径
    DNA Damage Repair
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