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NUMA1 抗体 (C-Term)

Cited in 1 publication. The 兔 多克隆 anti-NUMA1 antibody (ABIN2784222) specifically detects NUMA1 in WB. The antibody is reactive with 人, 小鼠, 大鼠, 豚鼠, 马, 犬, Cow 和 兔 samples.
产品编号 ABIN2784222
发货至: 中国
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Quick Overview for NUMA1 抗体 (C-Term) (ABIN2784222)

抗原

See all NUMA1 抗体
NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))

适用

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人, 小鼠, 大鼠, 豚鼠, 马, 犬, Cow, 兔

宿主

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兔

克隆类型

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多克隆

标记

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This NUMA1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    原理

    NUMA1 Antibody - C-terminal region

    序列

    AQRLQAQLNE LQAQLSQKEQ AAEHYKLQME KAKTHYDAKK QQNQELQEQL

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against NUMA1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human NUMA1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50532-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • Kilpivaara, Rantanen, Tamminen, Aittomäki, Blomqvist, Nevanlinna: "Comprehensive analysis of NuMA variation in breast cancer." in: BMC cancer, Vol. 8, pp. 71, (2008) (PubMed).

  • 抗原

    NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))

    别名

    NUMA1

    背景

    Background Information: NuMA is a structural element in maintaining nuclear integrity. A critical spindle pole-associated mechanism, called the END (Emi1/NuMA/dynein-dynactin) network, spatially restricts APC/C activity in early mitosis. The entire coding region and exon-intron boundaries of NuMa were screened in 92 familial breast cancer patients. But the results do not support the role of NuMA variants as breast cancer susceptibility alleles.

    Gene Name: Nuclear mitotic apparatus protein 1

    Alternative Symbols: NUMA, NMP-22

    Protein Name: Nuclear mitotic apparatus protein 1

    分子量

    238kDa

    基因ID

    4926

    NCBI登录号

    NP_006176

    UniProt

    Q14980

    途径

    Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, M Phase
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