ING1 抗体 (C-Term)
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北京 101111
Quick Overview for ING1 抗体 (C-Term) (ABIN2784213)
抗原
See all ING1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- ING1 Antibody - C-terminal region
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序列
- EKKAKTSKKK KRSKAKAERE ASPADLPIDP NEPTYCLCNQ VSYGEMIGCD
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against ING1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human ING1
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8103042
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- ING1 (Inhibitor of Growth Family, Member 1 (ING1))
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别名
- ING1
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背景
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Background Information: ING1 is a tumor suppressor protein that can induce cell growth arrest and apoptosis. The protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of ING1 gene have been detected in various cancers.This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
Gene Name: Inhibitor of growth family, member 1
Alternative Symbols: p33, p47, p33ING1, p24ING1c, p33ING1b, p47ING1a
Protein Name: Inhibitor of growth protein 1
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分子量
- 32kDa
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基因ID
- 3621
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NCBI登录号
- NP_937862
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UniProt
- Q5T9H0
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途径
- Protein targeting to Nucleus, Autophagy
抗原
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