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ING1 抗体 (C-Term)

This anti-ING1 antibody is a 兔 多克隆 antibody detecting ING1 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 斑马鱼, 马 和 兔.
产品编号 ABIN2784213
发货至: 中国

Quick Overview for ING1 抗体 (C-Term) (ABIN2784213)

抗原

See all ING1 抗体
ING1 (Inhibitor of Growth Family, Member 1 (ING1))

适用

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人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 斑马鱼, 马, 兔

宿主

  • 56
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克隆类型

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多克隆

标记

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This ING1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    EKKAKTSKKK KRSKAKAERE ASPADLPIDP NEPTYCLCNQ VSYGEMIGCD

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%

    产品特性

    This is a rabbit polyclonal antibody against ING1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human ING1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 279 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    ING1 (Inhibitor of Growth Family, Member 1 (ING1))

    别名

    ING1

    背景

    ING1 is a tumor suppressor protein that can induce cell growth arrest and apoptosis. The protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of ING1 gene have been detected in various cancers.This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
    Alias Symbols: p24ING1c, p33, p33ING1, p33ING1b, p47, p47ING1a
    Protein Interaction Partner: SIRT1, SIRT2, UBC, HDAC1, KIAA0101, PCNA, RBP1, RBBP7, RBBP4, HDAC2, BRMS1L, SIN3A, BRMS1, SAP30, ELAVL1, SMURF1, COPS2, NQO1, HIST2H3C, MRGBP, YWHAZ, YWHAH, YWHAG, YWHAE, YWHAB, KPNA2, KPNB1, YWHAQ, SFN, ESR1, LMNA, CDKN2A, TP53, KAT2B, DMAP1, EP300, HHT
    Protein Size: 279

    分子量

    32 kDa

    基因ID

    3621

    NCBI登录号

    NM_198219, NP_937862

    UniProt

    Q5T9H0

    途径

    Protein targeting to Nucleus, Autophagy
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