SPOP-B 抗体 (C-Term)
Quick Overview for SPOP-B 抗体 (C-Term) (ABIN2784150)
抗原
See all SPOP-B 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
序列
- YHASDVLETS GWKSMVVSHP HLVAEAYRSL ASAQCPFLGP PRKRLKQS
-
预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
-
产品特性
- This is a rabbit polyclonal antibody against SPOP. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human SPOP
-
-
anti-Speckle-Type POZ Protein (SPOP-B) (Internal Region) antibody
SPOP-B 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (AA 301-374) antibodySPOP-B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E2 unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (AA 1-374) antibodySPOP-B 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (Center) antibodySPOP-B 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (AA 48-374) antibodySPOP-B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (AA 74-107), (N-Term) antibodySPOP-B 适用: 小鼠, 斑马鱼 WB 宿主: 兔 Polyclonal RB49885 unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (AA 1-374) antibodySPOP-B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (C-Term) antibodySPOP-B 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 马, 兔, 小鸡, 非洲爪蟾, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (AA 1-193) antibodySPOP-B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (AA 175-374) antibodySPOP-B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 374 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- SPOP-B (Speckle-Type POZ Protein (SPOP-B))
-
别名
- SPOP
-
背景
-
SPOP may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein.
Alias Symbols: TEF2
Protein Interaction Partner: CUL3, SPOP, DEK, GLI2, AR, ATM, RXRB, MYD88, DAXX, NCOA3, SRRM1, GIT2, FADD, PIAS1, UBC, UBE2E3, PIP4K2B, ESR1, BMI1, RTN3, H2AFY, DPPA2, ZBTB16, HCST, TRAF1, PDX1, DDIT3, TRAF6, SIRT2, DOK2, PIP5K1B, GDI1, KPNA6,
Protein Size: 374 -
分子量
- 42 kDa
-
基因ID
- 8405
-
NCBI登录号
- NM_001007226, NP_001007227
-
UniProt
- O43791
抗原
-
