PCDH15 抗体 (N-Term)
Quick Overview for PCDH15 抗体 (N-Term) (ABIN2784074)
抗原
See all PCDH15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- HSIVVQVQCI NKKVGTIIYH EVRIVVRDRN DNSPTFKHES YYATVNELTP
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预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against PCDH15. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PCDH15
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 719 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PCDH15 (Protocadherin-15 (PCDH15))
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别名
- PCDH15
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背景
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PCDH15 is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. PCDH15 consists of a signal peptide, 11 extracellular calcium-binding domains, a transmembrane domain and a unique cytoplasmic domain. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene have been associated with hearing loss, which is consistent with its location at the Usher syndrome type 1F (USH1F) critical region on chromosome 10.
Alias Symbols: RP11-449J3.2, DFNB23, DKFZp667A1711, USH1F, CDHR15
Protein Interaction Partner: Dlg4,
Protein Size: 719 -
分子量
- 80 kDa
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基因ID
- 65217
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NCBI登录号
- NM_001142763
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UniProt
- A2A3E5
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途径
- Sensory Perception of Sound
抗原
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