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ORAI1 抗体 (Middle Region)

This anti-ORAI1 antibody is a 兔 多克隆 antibody detecting ORAI1 in WB. Suitable for 人, 大鼠, 马, Pig, Cow, 犬, 兔 和 Saccharomyces cerevisiae.
产品编号 ABIN2784058
发货至: 中国

Quick Overview for ORAI1 抗体 (Middle Region) (ABIN2784058)

抗原

See all ORAI1 抗体
ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))

适用

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人, 大鼠, 马, Pig, Cow, 犬, 兔, Saccharomyces cerevisiae

宿主

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克隆类型

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多克隆

标记

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This ORAI1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    IGTLLFLAEV VLLCWVKFLP LKKQPGQPRP TSKPPASGAA ANVSTSGITP

    预测反应

    Cow: 93%, Dog: 100%, Horse: 93%, Human: 100%, Pig: 100%, Rabbit: 100%, Rat: 86%, Yeast: 77%

    产品特性

    This is a rabbit polyclonal antibody against ORAI1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human ORAI1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 301 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))

    别名

    ORAI1

    背景

    ORAI1 belongs to the Orai family. ORAI1 (CRACM1) is a plasma membrane protein essential for store-operated calcium entry. Defects in ORAI1 are a cause of severe combined immunodeficiency with CRAC channel dysfunction (CRAC-SCID).CRACM1 is a plasma membrane protein essential for store-operated calcium entry (Vig et al., 2006 [PubMed 16645049]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-331 BC075831.1 1-331 332-844 BC013386.1 220-732 845-990 BC075831.1 845-990 991-1490 BG574128.1 52-551 1491-1496 AK027372.1 1235-1240
    Alias Symbols: CRACM1, FLJ14466, TMEM142A, ORAT1
    Protein Interaction Partner: UBQLN1, UBC, TRPC3, TRPC6,
    Protein Size: 301

    分子量

    33 kDa

    基因ID

    84876

    NCBI登录号

    NM_032790, NP_116179

    UniProt

    Q96D31

    途径

    TCR Signaling, BCR Signaling
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