ORAI1 抗体 (Middle Region)
Quick Overview for ORAI1 抗体 (Middle Region) (ABIN2784058)
抗原
See all ORAI1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- IGTLLFLAEV VLLCWVKFLP LKKQPGQPRP TSKPPASGAA ANVSTSGITP
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预测反应
- Cow: 93%, Dog: 100%, Horse: 93%, Human: 100%, Pig: 100%, Rabbit: 100%, Rat: 86%, Yeast: 77%
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产品特性
- This is a rabbit polyclonal antibody against ORAI1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ORAI1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 301 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))
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别名
- ORAI1
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背景
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ORAI1 belongs to the Orai family. ORAI1 (CRACM1) is a plasma membrane protein essential for store-operated calcium entry. Defects in ORAI1 are a cause of severe combined immunodeficiency with CRAC channel dysfunction (CRAC-SCID).CRACM1 is a plasma membrane protein essential for store-operated calcium entry (Vig et al., 2006 [PubMed 16645049]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-331 BC075831.1 1-331 332-844 BC013386.1 220-732 845-990 BC075831.1 845-990 991-1490 BG574128.1 52-551 1491-1496 AK027372.1 1235-1240
Alias Symbols: CRACM1, FLJ14466, TMEM142A, ORAT1
Protein Interaction Partner: UBQLN1, UBC, TRPC3, TRPC6,
Protein Size: 301 -
分子量
- 33 kDa
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基因ID
- 84876
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NCBI登录号
- NM_032790, NP_116179
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UniProt
- Q96D31
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途径
- TCR Signaling, BCR Signaling
抗原
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