MANEA 抗体 (Middle Region)
Quick Overview for MANEA 抗体 (Middle Region) (ABIN2783932)
抗原
See all MANEA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- KVTFHIEPYS NRDDQNMYKN VKYIIDKYGN HPAFYRYKTK TGNALPMFYV
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预测反应
- Dog: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 92%, Rat: 100%, Zebrafish: 77%
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产品特性
- This is a rabbit polyclonal antibody against MANEA. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human MANEA
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anti-Mannosidase, Endo-alpha (MANEA) (AA 218-267) antibody
MANEA 适用: 人, 小鼠, 大鼠, 犬, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Mannosidase, Endo-alpha (MANEA) (AA 30-100) antibodyMANEA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mannosidase, Endo-alpha (MANEA) (Middle Region) antibodyMANEA 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 462 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MANEA (Mannosidase, Endo-alpha (MANEA))
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别名
- MANEA
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背景
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N-glycosylation of proteins is initiated in the endoplasmic reticulum (ER) by the transfer of the preassembled oligosaccharide glucose-3-mannose-9-N-acetylglucosamine-2 from dolichyl pyrophosphate to acceptor sites on the target protein by an oligosaccharyltransferase complex. This core oligosaccharide is sequentially processed by several ER glycosidases and by an endomannosidase (E.C. 3.2.1.130), such as MANEA, in the Golgi. MANEA catalyzes the release of mono-, di-, and triglucosylmannose oligosaccharides by cleaving the alpha-1,2-mannosidic bond that links them to high-mannose glycans.
Alias Symbols: DKFZp686D20120, FLJ12838, hEndo, ENDO
Protein Interaction Partner: UBC, DNM2, PRD, AMPH,
Protein Size: 462 -
分子量
- 54 kDa
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基因ID
- 79694
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NCBI登录号
- NM_024641, NP_078917
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UniProt
- Q5SRI9
抗原
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