SIGIRR 抗体 (C-Term)
Quick Overview for SIGIRR 抗体 (C-Term) (ABIN2783841)
抗原
See all SIGIRR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- PVFGEPSAPP HTSGVSLGES RSSEVDVSDL GSRNYSARTD FYCLVSKDDM
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against SIGIRR. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human SIGIRR
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anti-Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (AA 1-118) antibody
SIGIRR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (AA 1-118) antibodySIGIRR 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (AA 1-120) antibodySIGIRR 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (C-Term) antibodySIGIRR 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (AA 1-410) antibodySIGIRR 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (AA 1-410) antibodySIGIRR 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H8-2G3 unconjugated
anti-Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (AA 1-117) antibodySIGIRR 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (C-Term) antibodySIGIRR 适用: 人, 小鼠 WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (AA 334-358) antibodySIGIRR 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) (C-Term) antibodySIGIRR 适用: 人, 小鼠 WB, EIA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 224 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SIGIRR (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR))
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别名
- SIGIRR
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背景
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SIGIRR acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. It attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through a TIR-TIR domain interaction with TLR4. Through its extracellular domain it interferes with the heterodimerization of Il1R1 and IL1RAP.
Alias Symbols: MGC110992, TIR8
Protein Interaction Partner: APP, UBC, SIGIRR, TLR9, TLR5, TLR4, TRAF6, IRAK1, RPN1, IL1R1, ENO2,
Protein Size: 224 -
分子量
- 25 kDa
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基因ID
- 59307
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UniProt
- Q6IA17
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途径
- Toll-Like Receptors Cascades
抗原
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