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POLR2H 抗体 (N-Term)

This anti-POLR2H antibody is a 兔 多克隆 antibody detecting POLR2H in WB. Suitable for 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔 和 斑马鱼. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2783467
发货至: 中国

Quick Overview for POLR2H 抗体 (N-Term) (ABIN2783467)

抗原

See all POLR2H 抗体
POLR2H (Polymerase (RNA) II (DNA Directed) Polypeptide H (POLR2H))

适用

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人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 斑马鱼

宿主

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克隆类型

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多克隆

标记

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This POLR2H antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    DLGDKFRLVI ASTLYEDGTL DDGEYNPTDD RPSRADQFEY VMYGKVYRIE

    预测反应

    Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

    产品特性

    This is a rabbit polyclonal antibody against POLR2H. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human POLR2H
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 150 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • 抗原

    POLR2H (Polymerase (RNA) II (DNA Directed) Polypeptide H (POLR2H))

    别名

    POLR2H

    背景

    POLR2H is one of the essential subunits of RNA polymerase II that is shared by the other two eukaryotic DNA-directed RNA polymerases, I and III.This gene encodes one of the essential subunits of RNA polymerase II that is shared by the other two eukaryotic DNA-directed RNA polymerases, I and III. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. This gene encodes a member of the E2F transcription factor protein family. E2F family members play a crucial role in control of the cell cycle and of the action of tumor suppressor proteins. They are also a target of the transforming proteins of small DNA tumor viruses. Many E2F proteins contain several evolutionarily conserved domains: a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. The encoded protein of this gene is atypical because it lacks the transactivation and tumor suppressor protein association domains. It contains a modular suppression domain and is an inhibitor of E2F-dependent transcription. The protein is part of a multimeric protein complex that contains a histone methyltransferase and the transcription factors Mga and Max. Multiple transcript variants have been reported for this gene, but it has not been clearly demonstrated that they encode valid isoforms. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-400 AU142999.1 1-400 401-907 BI772069.1 287-793 908-1792 BC008348.1 928-1812 1793-3185 AC099344.4 111461-112853 c
    Alias Symbols: RPABC3, RPB17, RPB8, hsRPB8
    Protein Interaction Partner: TCEB3, SRC, PSMB9, ESR1, CEP57, RNF2, SNRNP200, SART3, POLR2E, DNMT3B, DNMT3A, BAG3, POLR2C, MED19, METTL18, MED26, UBC, POLR3D, POLR3H, POLR3B, POLR1A, POLR3A, POLR1C, NEDD8, Atf7ip, SUMO2, INTS10, POLR2D, POLR2A, BRCA1, BARD1, INTS5, INTS3, INTS6, INTS1
    Protein Size: 150

    分子量

    17 kDa

    基因ID

    5437

    NCBI登录号

    NM_006232, NP_006223

    UniProt

    P52434

    途径

    Regulatory RNA Pathways
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