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Dnmt2 抗体 (N-Term)

TRDMT1 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 兔, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2783440
发货至: 中国
  • 抗原 See all Dnmt2 (TRDMT1) 抗体
    Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))
    抗原表位
    • 15
    • 12
    • 8
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 小鼠, 大鼠, Cow, 犬, Pig, 兔, 豚鼠, 马
    宿主
    • 62
    • 7
    克隆类型
    • 64
    • 5
    多克隆
    标记
    • 31
    • 7
    • 6
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Dnmt2 antibody is un-conjugated
    应用范围
    • 43
    • 42
    • 31
    • 13
    • 13
    • 7
    • 7
    • 7
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    序列
    MILMSPPCQP FTRIGRQGDM TDSRTNSFLH ILDILPRLQK LPKYILLENV
    预测反应
    Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against TRDMT1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human TRDMT1
    Top Product
    Discover our top product TRDMT1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 391 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))
    别名
    TRDMT1 (TRDMT1 产品)
    别名
    MGC89267 antibody, DMNT2 antibody, DNMT2 antibody, MHSAIIP antibody, PUMET antibody, RNMT1 antibody, Dnmt2 antibody, Rnmt2 antibody, dnmt2 antibody, tRNA aspartic acid methyltransferase 1 antibody, tRNA aspartic acid methyltransferase 1 L homeolog antibody, trdmt1 antibody, TRDMT1 antibody, Trdmt1 antibody, trdmt1.L antibody
    背景
    CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. TRDMT1 is a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome.CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome. Alternative splicing results in multiple transcript variants encoding different isoforms.
    Alias Symbols: DNMT2, M.HsaIIP, PuMet, RNMT1, DMNT2, PUMET, MHSAIIP
    Protein Interaction Partner: TBC1D2B, SNRPD3, NFRKB, GBE1, APP, LRIF1, COPS6, RBM48, SETDB1, UTP14A, DDX24, UNC119, STX1A, EEF1A1,
    Protein Size: 391
    分子量
    44 kDa
    基因ID
    1787
    NCBI登录号
    NM_004412, NP_004403
    UniProt
    O14717
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