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Dnmt2 抗体 (N-Term)

The 兔 多克隆 anti-Dnmt2 antibody (ABIN2783440) specifically detects Dnmt2 in WB. The antibody is reactive with 人, 小鼠, 大鼠, Cow, 犬, Pig, 兔, 豚鼠 和 马 samples.
产品编号 ABIN2783440
发货至: 中国
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Quick Overview for Dnmt2 抗体 (N-Term) (ABIN2783440)

抗原

See all Dnmt2 (TRDMT1) 抗体
Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))

适用

人, 小鼠, 大鼠, Cow, 犬, Pig, 兔, 豚鼠, 马

宿主

  • 75
  • 7
兔

克隆类型

  • 77
  • 5
多克隆

标记

  • 33
  • 7
  • 6
  • 6
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Dnmt2 antibody is un-conjugated

应用范围

  • 46
  • 37
  • 28
  • 18
  • 13
  • 13
  • 7
  • 6
  • 3
  • 3
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 13
    • 8
    • 8
    • 7
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    原理

    TRDMT1 Antibody - N-terminal region

    序列

    MILMSPPCQP FTRIGRQGDM TDSRTNSFLH ILDILPRLQK LPKYILLENV

    预测反应

    Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against TRDMT1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human TRDMT1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48627-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))

    别名

    TRDMT1

    背景

    Background Information: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. TRDMT1 is a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome.CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome. Alternative splicing results in multiple transcript variants encoding different isoforms.

    Gene Name: TRNA aspartic acid methyltransferase 1

    Alternative Symbols: DMNT2, DNMT2, PUMET, RNMT1, MHSAIIP

    Protein Name: tRNA (cytosine(38)-C(5))-methyltransferase

    分子量

    45 kDa

    基因ID

    1787

    NCBI登录号

    NP_004403

    UniProt

    O14717
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