PYGB 抗体 (N-Term)
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北京 101111
Quick Overview for PYGB 抗体 (N-Term) (ABIN2783431)
抗原
See all PYGB (GPBB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- PYGB Antibody - N-terminal region
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序列
- QQHYYERDPK RIYYLSLEFY MGRTLQNTMV NLGLQNACDE AIYQLGLDLE
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预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against PYGB. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PYGB
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48586-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PYGB (GPBB) (phosphorylase, Glycogen, Brain (GPBB))
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别名
- PYGB
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背景
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Background Information: PYGB is a glycogen phosphorylase found predominantly in the brain. It forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Gene Name: Phosphorylase, glycogen, brain
Alternative Symbols: GPBB
Protein Name: Glycogen phosphorylase, brain form
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分子量
- 97 kDa
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基因ID
- 5834
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NCBI登录号
- NP_002853
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UniProt
- P11216
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途径
- Cellular Glucan Metabolic Process
抗原
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