Myosin 9 抗体 (Middle Region)
Quick Overview for Myosin 9 抗体 (Middle Region) (ABIN2783216)
抗原
See all Myosin 9 (MYH9) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- DAMNREVSSL KNKLRRGDLP FVVPRRMARK GAGDGSDEEV DGKADGAEAK
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预测反应
- Dog: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 86%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against MYH9. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human MYH9
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1960 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Dlc1 interaction with non-muscle myosin heavy chain II-A (Myh9) and Rac1 activation." in: Biology open, Vol. 5, Issue 4, pp. 452-60, (2016) (PubMed).
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: "Dlc1 interaction with non-muscle myosin heavy chain II-A (Myh9) and Rac1 activation." in: Biology open, Vol. 5, Issue 4, pp. 452-60, (2016) (PubMed).
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- Myosin 9 (MYH9)
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别名
- MYH9
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背景
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MYH9 is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain. The protein is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in MYH9 are the cause of non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.
Alias Symbols: DFNA17, EPSTS, FTNS, MGC104539, MHA, NMHC-II-A, NMMHCA, BDPLT6, NMMHC-IIA
Protein Interaction Partner: HUWE1, UBC, TP53, SUMO2, SUMO3, IVNS1ABP, LGR4, MDM2, RPA3, RPA2, RPA1, EED, MYL6, MYH14, CDC73, OTUD6B, AKAP10, MYL12A, MYL9, TARDBP, FN1, UBD, PIK3C3, ACE, CSNK2A1, ACTB, PAN2, ITGA4, HSP90AB1, HSP90AA1, ESR1, CASP4, IQCB1, VCAM1, PPP2CA, Fcho2, TRAF3IP
Protein Size: 1960 -
分子量
- 226 kDa
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基因ID
- 4627
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NCBI登录号
- NM_002473, NP_002464
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UniProt
- P35579
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Integrin Complex
抗原
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