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Myosin 9 抗体 (Middle Region)

There is 1 publication for this product available. The 兔 多克隆 anti-Myosin 9 antibody is suitable to detect Myosin 9 in samples from 人, 小鼠, 大鼠, 犬, Pig, 豚鼠 和 兔. It has been validated for WB.
产品编号 ABIN2783216
发货至: 中国
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Quick Overview for Myosin 9 抗体 (Middle Region) (ABIN2783216)

抗原

See all Myosin 9 (MYH9) 抗体
Myosin 9 (MYH9)

适用

  • 75
  • 21
  • 15
  • 2
  • 2
  • 1
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  • 1
人, 小鼠, 大鼠, 犬, Pig, 豚鼠, 兔

宿主

  • 60
  • 13
  • 2
  • 1
  • 1

克隆类型

  • 51
  • 26
多克隆

标记

  • 42
  • 6
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
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  • 1
This Myosin 9 antibody is un-conjugated

应用范围

  • 56
  • 38
  • 25
  • 17
  • 13
  • 11
  • 9
  • 6
  • 4
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 8
    • 7
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    DAMNREVSSL KNKLRRGDLP FVVPRRMARK GAGDGSDEEV DGKADGAEAK

    预测反应

    Dog: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 86%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against MYH9. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human MYH9
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 1960 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Sabbir, Dillon, Mowat: "Dlc1 interaction with non-muscle myosin heavy chain II-A (Myh9) and Rac1 activation." in: Biology open, Vol. 5, Issue 4, pp. 452-60, (2016) (PubMed).

  • 抗原

    Myosin 9 (MYH9)

    别名

    MYH9

    背景

    MYH9 is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain. The protein is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in MYH9 are the cause of non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.
    Alias Symbols: DFNA17, EPSTS, FTNS, MGC104539, MHA, NMHC-II-A, NMMHCA, BDPLT6, NMMHC-IIA
    Protein Interaction Partner: HUWE1, UBC, TP53, SUMO2, SUMO3, IVNS1ABP, LGR4, MDM2, RPA3, RPA2, RPA1, EED, MYL6, MYH14, CDC73, OTUD6B, AKAP10, MYL12A, MYL9, TARDBP, FN1, UBD, PIK3C3, ACE, CSNK2A1, ACTB, PAN2, ITGA4, HSP90AB1, HSP90AA1, ESR1, CASP4, IQCB1, VCAM1, PPP2CA, Fcho2, TRAF3IP
    Protein Size: 1960

    分子量

    226 kDa

    基因ID

    4627

    NCBI登录号

    NM_002473, NP_002464

    UniProt

    P35579

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling, Integrin Complex
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