SETD2 抗体 (N-Term)
Quick Overview for SETD2 抗体 (N-Term) (ABIN2783051)
抗原
See all SETD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- SDEDSVRTSS SQRSHDLKFS ASIEKERDFK KSSAPLKSED LGKPSRSKTD
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交叉反应
- 犬, 人, 大鼠
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预测反应
- Cow: 79%, Dog: 86%, Horse: 86%, Human: 100%, Mouse: 83%, Rat: 85%
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产品特性
- This is a rabbit polyclonal antibody against SETD2. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SETD2
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 891 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Promoter-exon relationship of H3 lysine 9, 27, 36 and 79 methylation on pluripotency-associated genes." in: Biochemical and biophysical research communications, Vol. 401, Issue 4, pp. 611-7, (2010) (PubMed).
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: "Promoter-exon relationship of H3 lysine 9, 27, 36 and 79 methylation on pluripotency-associated genes." in: Biochemical and biophysical research communications, Vol. 401, Issue 4, pp. 611-7, (2010) (PubMed).
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- SETD2 (SET Domain Containing 2 (SETD2))
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别名
- SETD2 / HIF1
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背景
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Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. SETD2 is a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs.
Alias Symbols: FLJ16420, FLJ22472, FLJ23184, FLJ45883, HIF-1, HSPC069, HYPB, KIAA1732, KMT3A, SET2, HIP-1, HBP231, p231HBP
Protein Interaction Partner: CLK2, SOX2, CBX8, HCVgp1, SIAH2, SMAD3, CIC, ATXN1, ELAVL1, UBC, SETD2, HIST1H3A, POLR2A, TP53, IWS1, HTT,
Protein Size: 891 -
分子量
- 97 kDa
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基因ID
- 29072
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NCBI登录号
- NM_014159
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UniProt
- Q9BYW2
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途径
- Tube Formation
抗原
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