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BMP10 抗体 (C-Term)

This anti-BMP10 antibody is a 兔 多克隆 antibody detecting BMP10 in WB. Suitable for 人, 小鼠, 大鼠, 犬, 兔, Cow, 马 和 豚鼠.
产品编号 ABIN2782814
发货至: 中国

Quick Overview for BMP10 抗体 (C-Term) (ABIN2782814)

抗原

See all BMP10 抗体
BMP10 (Bone Morphogenetic Protein 10 (BMP10))

适用

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人, 小鼠, 大鼠, 犬, 兔, Cow, 马, 豚鼠

宿主

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克隆类型

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多克隆

标记

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This BMP10 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    GYEAYECRGV CNYPLAEHLT PTKHAIIQAL VHLKNSQKAS KACCVPTKLE

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against BMP10. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C-terminal region of Human BMP10
  • 限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeat freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    BMP10 (Bone Morphogenetic Protein 10 (BMP10))

    别名

    BMP10

    背景

    BMP10 is required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. It acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth.
    Alias Symbols: -
    Protein Interaction Partner: BMPR2, ACVR2B, ACVR2A, SERINC3,
    Protein Size: 424

    分子量

    46 kDa

    基因ID

    27302

    NCBI登录号

    NM_014482, NP_055297

    UniProt

    O95393

    途径

    Hormone Activity, Regulation of Muscle Cell Differentiation
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