BMP10 抗体 (N-Term)
Quick Overview for BMP10 抗体 (N-Term) (ABIN2782813)
抗原
See all BMP10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- KFATDRTSMP SANIIRSFKN EDLFSQPVSF NGIRKYPLLF NVSIPHHEEV
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预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against Bmp10. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide corresponding to a region of Rat
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 421 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- BMP10 (Bone Morphogenetic Protein 10 (BMP10))
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别名
- Bmp10
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背景
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Bmp10 is required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Bmp10 acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Bmp10 inhibits endothelial cell migration and growth.
Alias Symbols: Bmp10
Protein Size: 421 -
分子量
- 48 kDa
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基因ID
- 500245
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NCBI登录号
- NM_001031824, NP_001026994
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UniProt
- Q4AEG6
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途径
- Hormone Activity, Regulation of Muscle Cell Differentiation
抗原
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