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BACE2 抗体 (N-Term)

This 兔 多克隆 anti-BACE2 antibody specifically detects BACE2 in WB. The antibody is reactive with 人, 大鼠, 小鼠, 豚鼠 和 Cow samples.
产品编号 ABIN2782768
发货至: 中国
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Quick Overview for BACE2 抗体 (N-Term) (ABIN2782768)

抗原

See all BACE2 抗体
BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))

适用

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人, 大鼠, 小鼠, 豚鼠, Cow

宿主

  • 64
  • 5
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克隆类型

  • 66
  • 7
多克隆

标记

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This BACE2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    PAGAANFLAM VDNLQGDSGR GYYLEMLIGT PPQKLQILVD TGSSNFAVAG

    预测反应

    Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against BACE2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human BACE2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 396 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))

    别名

    BACE2

    背景

    Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by this gene. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene.
    Alias Symbols: AEPLC, ALP56, ASP1, ASP21, BAE2, CDA13, CEAP1, DRAP
    Protein Interaction Partner: UBC, BACE2, APP, GGA1, GGA2,
    Protein Size: 396

    分子量

    37 kDa

    基因ID

    25825

    NCBI登录号

    NM_138992, NP_620477

    UniProt

    Q9Y5Z0
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