SPTLC1 抗体 (Middle Region)
Quick Overview for SPTLC1 抗体 (Middle Region) (ABIN2782713)
抗原
See all SPTLC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- ICPLPELVKL KYKYKARIFL EESLSFGVLG EHGRGVTEHY GINIDDIDLI
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against SPTLC1. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human SPTLC1
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anti-serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1) (C-Term) antibody
SPTLC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1) (AA 143-473) antibodySPTLC1 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1) (AA 37-310) antibodySPTLC1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1) (AA 43-143) antibodySPTLC1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D11 unconjugated
anti-serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1) (AA 254-303) antibodySPTLC1 适用: 人, 小鼠, 大鼠, 兔, 豚鼠, 猴, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1) (AA 216-265) antibodySPTLC1 适用: 人, 小鼠, 大鼠, Cow, 兔, 豚鼠, 马, 斑马鱼, 猴, Hamster, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1) (AA 138-154), (Middle Region) antibodySPTLC1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1) (AA 405-437), (C-Term) antibodySPTLC1 适用: 人 WB 宿主: 兔 Polyclonal RB4727 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 473 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
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别名
- SPTLC1
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背景
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Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. SPTLC1 is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in SPTLC1 gene were identified in patients with hereditary sensory neuropathy type 1.Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. The product of this gene is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified.
Alias Symbols: HSAN, HSAN1, HSN1, LBC1, LCB1, MGC14645, SPT1, SPTI, hLCB1
Protein Interaction Partner: UBC, FBXO6, EGFR, ADRB2, CFTR, ABCA1, UBD, AUP1, MYC, ATG4C, ORMDL3, SPTLC2, C20orf24, MAGED1, RGS20,
Protein Size: 473 -
分子量
- 53 kDa
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基因ID
- 10558
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NCBI登录号
- NM_006415, NP_006406
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UniProt
- O15269
抗原
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