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TMPRSS11D 抗体 (N-Term)

TMPRSS11D 适用: 人, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782621
发货至: 中国
  • 抗原 See all TMPRSS11D 抗体
    TMPRSS11D (Transmembrane Protease, serine 11D (TMPRSS11D))
    抗原表位
    • 15
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 33
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 豚鼠, 马, 兔
    宿主
    • 29
    • 3
    • 1
    克隆类型
    • 32
    • 1
    多克隆
    标记
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TMPRSS11D antibody is un-conjugated
    应用范围
    • 13
    • 13
    • 12
    • 10
    • 6
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    RSSFQLLNVE YNSQLNSPAT QEYRTLSGRI ESLITKTFKE SNLRNQFIRA
    预测反应
    Guinea Pig: 79%, Horse: 79%, Human: 100%, Rabbit: 79%
    产品特性
    This is a rabbit polyclonal antibody against TMPRSS11D. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human TMPRSS11D
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 418 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Matsushima, Takahashi, Nakaya, Maezawa, Miki, Nakamura, Ohgushi, Yasuoka: "Human airway trypsin-like protease stimulates human bronchial fibroblast proliferation in a protease-activated receptor-2-dependent pathway." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 290, Issue 2, pp. L385-95, (2006) (PubMed).

  • 抗原
    TMPRSS11D (Transmembrane Protease, serine 11D (TMPRSS11D))
    别名
    TMPRSS11D (TMPRSS11D 产品)
    别名
    HAT antibody, AST antibody, AsP antibody, BC020151 antibody, Asp antibody, Tmprss11d antibody, transmembrane protease, serine 11D antibody, transmembrane protease, serine 11d antibody, transmembrane protease serine 11D antibody, TMPRSS11D antibody, Tmprss11d antibody, LOC100720850 antibody
    背景
    TMPRSS11D is a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38 % identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.This gene encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38 % identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.
    Alias Symbols: HAT, MGC150587, MGC150588
    Protein Size: 418
    分子量
    46 kDa
    基因ID
    9407
    NCBI登录号
    NM_004262, NP_004253
    UniProt
    O60235
    途径
    Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process
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