RMI1 抗体 (N-Term)
Quick Overview for RMI1 抗体 (N-Term) (ABIN2782588)
抗原
See all RMI1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- DGILEIPKGE LNGFYALQIN SLVDVSQPAY SQIQKLRGKN TTNDLVTAEA
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预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against RMI1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human RMI1
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anti-Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1) (AA 1-470) antibody
RMI1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1) (AA 181-443) antibodyRMI1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1) (AA 1-379) antibodyRMI1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1) (AA 71-120) antibodyRMI1 适用: 人, 小鼠, 犬, 马, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1) (AA 1-350) antibodyRMI1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1) antibodyRMI1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 625 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RMI1 (Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1))
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别名
- RMI1
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背景
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RMI1 is an essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. RMI1 promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. RMI1 is required for BLM phosphorylation during mitosis. Within the BLM complex, RMI1 is required for BLM and TOP3A stability.RMI1 is a component of protein complexes that limit DNA crossover formation via the dissolution of double Holliday junctions (Raynard et al., 2006 [PubMed 16595695]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-136 BP327553.1 1-136 137-885 DN997105.1 9-757 886-2740 AL732446.4 14777-16631 2741-3508 BC039999.2 2566-3333
Alias Symbols: BLAP75, C9orf76, FLJ12888, RP11-346I8.1
Protein Interaction Partner: APITD1, STRA13, UBC, RPA3, RPA2, RPA1, TOPBP1, BLM, NR1H2, UBE3A, HSPA13, PFDN1, Ercc6l, Top3a, FANCM, RMI2, FANCF, RMI1, FANCA,
Protein Size: 625 -
分子量
- 70 kDa
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基因ID
- 80010
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NCBI登录号
- NM_024945, NP_079221
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UniProt
- Q9H9A7
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途径
- DNA Damage Repair
抗原
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