PSME3 抗体 (C-Term)
Quick Overview for PSME3 抗体 (C-Term) (ABIN2782512)
抗原
See all PSME3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- TVTEIDEKEY ISLRLIISEL RNQYVTLHDM ILKNIEKIKR PRSSNAETLY
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against PSME3. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human PSME3
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anti-PSME3 (PSME3) (AA 7-254) antibody
PSME3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-PSME3 (PSME3) antibodyKO Validated PSME3 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-PSME3 (PSME3) (AA 2-252) antibodyPSME3 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-PSME3 (PSME3) antibodyPSME3 适用: 人, 大鼠, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-PSME3 (PSME3) (AA 1-254) antibodyPSME3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-PSME3 (PSME3) (C-Term) antibodyPSME3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-PSME3 (PSME3) (N-Term) antibodyPSME3 适用: 人, 大鼠, 小鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-PSME3 (PSME3) (N-Term) antibodyPSME3 适用: 人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-PSME3 (PSME3) (AA 48-97) antibodyPSME3 适用: 人, 大鼠, 小鼠, 犬, Pig, Cow, 豚鼠, 马, 兔, Bat, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-PSME3 (PSME3) (N-Term) antibodyPSME3 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 254 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PSME3
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别名
- PSME3
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背景
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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. PSME3 is the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring. Two transcript variants encoding different isoforms have been identified.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring. Two transcript variants encoding different isoforms have been identified.
Alias Symbols: Ki, PA28-gamma, PA28G, REG-GAMMA
Protein Interaction Partner: SPG7, PRKAB2, PFDN5, BBS2, TNFAIP8L1, EAF1, ZCCHC10, PRR13, TXN2, FBXO7, DIP2A, PSME3, HUWE1, TUBGCP3, SIRT1, CREBBP, PSMD14, SHFM1, GTPBP4, MDM2, ADARB2, C1QBP, PARK2, CLK3, CLK2, YWHAQ, TBXA2R, BAG3, NPM1, ITGA4, CBX2, vpr, vif, HCVgp1, CBX4, VCAM1, UBC
Protein Size: 254 -
分子量
- 29 kDa
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基因ID
- 10197
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NCBI登录号
- NM_005789, NP_005780
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UniProt
- P61289
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途径
- Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Hepatitis C, Synthesis of DNA
抗原
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