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Lamin B1 抗体 (Middle Region)

This anti-Lamin B1 antibody is a 兔 多克隆 antibody detecting Lamin B1 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 兔, 犬, 马 和 豚鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2782509
发货至: 中国

Quick Overview for Lamin B1 抗体 (Middle Region) (ABIN2782509)

抗原

See all Lamin B1 (LMNB1) 抗体
Lamin B1 (LMNB1)

适用

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人, 小鼠, 大鼠, Cow, 兔, 犬, 马, 豚鼠

宿主

  • 54
  • 35
  • 1

克隆类型

  • 52
  • 38
多克隆

标记

  • 79
  • 2
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This Lamin B1 antibody is un-conjugated

应用范围

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  • 15
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  • 9
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  • 2
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  • 1
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Western Blotting (WB)
  • 抗原表位

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    • 1
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    • 1
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    Middle Region

    序列

    EEVAQRSTVF KTTIPEEEEE EEEAAGVVVE EELFHQQGTP RASNRSCAIM

    预测反应

    Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 91%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against LMNB1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human LMNB1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 586 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lee, Seng, Sekine, Hinton, Fu, Avraham, Avraham: "Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1." in: PLoS medicine, Vol. 4, Issue 6, pp. e186, (2007) (PubMed).

  • 抗原

    Lamin B1 (LMNB1)

    别名

    LMNB1

    背景

    LAMNB1 encodes for one of the two B type proteins of the nuclear lamina, B1. The Vertebrate lamins consist of two types, A and B. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression.The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ADLD, LMN, LMN2, LMNB, MGC111419
    Protein Interaction Partner: POU2F1, SPRTN, UBC, SUMO2, SUMO3, MDM2, EED, ACTR10, NCAPH, ZZEF1, DCTN3, DCTN2, ACTR1A, ACTR1B, PARK2, HECW2, YWHAQ, ADRB2, LMNA, MELK, URB2, FN1, ATF4, SERPINA3, ABCG8, MBIP, GIT2, WHSC1, VCAM1, ITGA4, PRKCB, CDK1, MAGT1, HP1BP3, NCSTN, HNRNPM, EIF6, IL
    Protein Size: 586

    分子量

    66 kDa

    基因ID

    4001

    NCBI登录号

    NM_005573, NP_005564

    UniProt

    P20700

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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