PLK1 抗体 (Polo-Like Kinase 1) (C-Term)

Details for Product anti-PLK1 Antibody No. ABIN2782496, 供应商: Log in to see
抗原
  • PLK
  • STPK13
  • plk
  • PLK-1
  • Plx1
  • stpk13
  • Plk
  • cb525
  • cb636
  • ik:tdsubc_2d1
  • wu:fb37g11
  • wu:fb76g03
  • xx:tdsubc_2d1
  • polo like kinase 1
  • polo like kinase 1 S homeolog
  • polo-like kinase 1
  • polo-like kinase 1 (Drosophila)
  • Serine/threonine-protein kinase plk-1
  • PLK1
  • plk1.S
  • plk1
  • Plk1
  • plk-1
抗原表位
C-Term
49
41
22
16
15
15
14
9
8
7
6
6
6
5
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
适用
牛, 犬, 豚鼠, 马, 人, 小鼠, 兔, 大鼠
359
153
88
65
19
17
12
12
11
6
3
3
2
2
2
2
1
1
1
1
1
1
1
宿主

193
173
17
克隆类型
多克隆
标记
This PLK1 antibody is un-conjugated
13
12
11
10
9
9
9
6
6
6
6
6
6
6
6
6
5
4
4
2
2
2
2
2
2
2
2
2
应用范围
Immunohistochemistry (IHC), Western Blotting (WB)
320
186
90
80
71
49
47
34
27
5
4
4
3
3
2
2
2
选项
Supplier
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Supplier Product No.
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免疫原 The immunogen is a synthetic peptide directed towards the C terminal region of human PLK1
Blocking Peptide Blocking peptide for this product available: ABIN981865
序列 KRDFRTYRLS LLEEYGCCKE LASRLRYART MVDKLLSSRS ASNRLKAS
预测反应 Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%
产品特性 This is a rabbit polyclonal antibody against PLK1. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Affinity Purified
别名 PLK1 (PLK1 Antibody 摘要)
背景 Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of APC/C inhibitors, and the regulation of mitotic exit and cytokinesis.
Alias Symbols: PLK, STPK13
Protein Interaction Partner: RAP1GAP, CHFR, KLHL22, BRCA1, BORA, EGFR, UBC, NUAK1, MUS81, FBXO6, PPP6R2, STK3, BUB1B, FZR1, CDC20, CHEK2, TP53BP1, CDCA5, LATS1, CENPU, CDC25C, KLHL21, OFD1, CUL2, Sugt1, KRBA1, HSPA4, PHC2, KLHL9, FLJ20712, RABAC1, TANK, RBX1, VCP, CDH1, APP, STAG2, N
Protein Size: 603
分子量 68 kDa
基因ID 5347
NCBI登录号 NM_005030, NP_005021
UniProt P53350
途径 Cell Division Cycle, M Phase
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 603 AA

限制 仅限研究用
状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
厂商提供的图像
Immunohistochemistry (IHC) image for anti-Polo-Like Kinase 1 (PLK1) (C-Term) antibody (ABIN2782496) anti-Polo-Like Kinase 1 (PLK1) (C-Term) antibody
背景 Yamashiro, Yamakita, Totsukawa, Goto, Kaibuchi, Ito, Hartshorne, Matsumura: "Myosin phosphatase-targeting subunit 1 regulates mitosis by antagonizing polo-like kinase 1." in: Developmental cell, Vol. 14, Issue 5, pp. 787-97, 2008 (PubMed).

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