PLK1 抗体 (C-Term)
Quick Overview for PLK1 抗体 (C-Term) (ABIN2782496)
抗原
See all PLK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- KRDFRTYRLS LLEEYGCCKE LASRLRYART MVDKLLSSRS ASNRLKAS
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against PLK1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human PLK1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 603 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PLK1 (Polo-Like Kinase 1 (PLK1))
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别名
- PLK1
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背景
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Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of APC/C inhibitors, and the regulation of mitotic exit and cytokinesis.
Alias Symbols: PLK, STPK13
Protein Interaction Partner: RAP1GAP, CHFR, KLHL22, BRCA1, BORA, EGFR, UBC, NUAK1, MUS81, FBXO6, PPP6R2, STK3, BUB1B, FZR1, CDC20, CHEK2, TP53BP1, CDCA5, LATS1, CENPU, CDC25C, KLHL21, OFD1, CUL2, Sugt1, KRBA1, HSPA4, PHC2, KLHL9, FLJ20712, RABAC1, TANK, RBX1, VCP, CDH1, APP, STAG2, N
Protein Size: 603 -
分子量
- 68 kDa
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基因ID
- 5347
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NCBI登录号
- NM_005030, NP_005021
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UniProt
- P53350
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途径
- Cell Division Cycle, M Phase
抗原
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