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Non-Syndromic Hearing Impairment Protein 5 (GSDME) (C-Term) 抗体

The 兔 多克隆 anti-Non-Syndromic Hearing Impairment Protein 5 antibody is suitable to detect Non-Syndromic Hearing Impairment Protein 5 in samples from 人, 大鼠, 犬, 豚鼠 和 Cow. It has been validated for WB 和 IHC.
产品编号 ABIN2782489
发货至: 中国
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Quick Overview for Non-Syndromic Hearing Impairment Protein 5 (GSDME) (C-Term) 抗体 (ABIN2782489)

抗原

Non-Syndromic Hearing Impairment Protein 5 (GSDME)

适用

人, 大鼠, 犬, 豚鼠, Cow

宿主

  • 27
  • 1
兔

克隆类型

  • 24
  • 4
多克隆

标记

  • 14
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
非结合性

应用范围

  • 15
  • 12
  • 11
  • 8
  • 5
  • 3
  • 3
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 12
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    GSDME Antibody - C-terminal region

    序列

    AALLGTCCKL QIIPTLCHLL RALSDDGVSD LEDPTLTPLK DTERFGIVQR

    预测反应

    Cow: 85%, Dog: 77%, Guinea Pig: 83%, Human: 100%, Rat: 85%

    产品特性

    This is a rabbit polyclonal antibody against DFNA5. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human DFNA5
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46106-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Non-Syndromic Hearing Impairment Protein 5 (GSDME)

    别名

    GSDME

    背景

    Background Information: Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene.

    Gene Name: gasdermin E

    Alternative Symbols: DFNA5, ICERE-1

    Protein Name: gasdermin-E

    分子量

    47kDa

    基因ID

    1687

    UniProt

    A4FVA8
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