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RRM2B 抗体 (Middle Region)
RRM2B
适用: 人, 大鼠, 小鼠, 兔, Cow, 马, Pig, 犬, 豚鼠, Saccharomyces cerevisiae, 斑马鱼
WB
宿主: 兔
Polyclonal
unconjugated
RRM2B抗体详情
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抗原
See all RRM2B 抗体
RRM2B
(Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
抗原表位
All epitopes for RRM2B 抗体
Middle Region
适用
All reactivities for RRM2B 抗体
人, 大鼠, 小鼠, 兔, Cow, 马, Pig, 犬, 豚鼠, Saccharomyces cerevisiae, 斑马鱼
宿主
All hosts for RRM2B 抗体
兔
克隆类型
All clonalities for RRM2B 抗体
多克隆
标记
All conjugates for RRM2B 抗体
This RRM2B antibody is un-conjugated
应用范围
All applications for RRM2B 抗体
Western Blotting (WB)
序列
VHSEMYSLLI DTYIRDPKKR EFLFNAIETM PYVKKKADWA LRWIADRKST
预测反应
Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 100%, Rat: 93%, Yeast: 93%, Zebrafish: 93%
产品特性
This is a rabbit polyclonal antibody against RRM2B. It was validated on Western Blot.
纯化方法
Affinity Purified
免疫原
The immunogen is a synthetic peptide directed towards the middle region of Human RRM2B
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Discover our top product RRM2B Primary Antibody
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
缓冲液
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeat freeze-thaw cycles.
储存条件
-20 °C
储存方法
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
RRM2B目标详情
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抗原
RRM2B
(Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
别名
RRM2B (RRM2B 产品 )
别名
p53r2 antibody, RRM2B antibody, MTDPS8A antibody, MTDPS8B antibody, P53R2 antibody, p53R2 antibody, ribonucleotide reductase M2 B (TP53 inducible) S homeolog antibody, ribonucleotide reductase regulatory TP53 inducible subunit M2B antibody, ribonucleotide reductase M2 B (TP53 inducible) antibody, rrm2b.S antibody, RRM2B antibody, rrm2b antibody, Rrm2b antibody
背景
This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described. Protein Interaction Partner: RRM2B, ORC4, UBC, AICDA, RRM1, TP53, RRM2, MDM2, ATM, ZBTB17, MYC, Protein Size: 299
分子量
32 kDa
基因ID
50484
途径
p53 Pathway , Negative Regulation of intrinsic apoptotic Signaling
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