RRM2B 抗体 (Middle Region)
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北京 101111
Quick Overview for RRM2B 抗体 (Middle Region) (ABIN2782441)
抗原
See all RRM2B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- VHSEMYSLLI DTYIRDPKKR EFLFNAIETM PYVKKKADWA LRWIADRKST
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 100%, Rat: 93%, Yeast: 93%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against RRM2B. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of Human RRM2B
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anti-Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (AA 3-84) antibody
RRM2B 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 6C1 unconjugated
anti-Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (AA 1-351) antibodyRRM2B 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (N-Term) antibodyRRM2B 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (AA 3-84) antibodyRRM2B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6C1 unconjugated
anti-Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (N-Term) antibodyRRM2B 适用: 人 WB, ELISA, IHC, IP, FM 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (AA 2-17), (N-Term) antibodyRRM2B 适用: 人, 大鼠, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
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别名
- RRM2B
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背景
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This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.
Protein Interaction Partner: RRM2B, ORC4, UBC, AICDA, RRM1, TP53, RRM2, MDM2, ATM, ZBTB17, MYC,
Protein Size: 299 -
分子量
- 32 kDa
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基因ID
- 50484
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途径
- p53 Pathway, Negative Regulation of intrinsic apoptotic Signaling
抗原
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