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SOD1 抗体 (N-Term)

This anti-SOD1 antibody is a 兔 多克隆 antibody detecting SOD1 in WB 和 IHC. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2782351
发货至: 中国

Quick Overview for SOD1 抗体 (N-Term) (ABIN2782351)

抗原

See all SOD1 抗体
SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

适用

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宿主

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克隆类型

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多克隆

标记

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This SOD1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    序列

    MATKAVCVLK GDGPVQGIIN FEQKESNGPV KVWGSIKGLT EGLHGFHVHE

    预测反应

    Human: 100%

    产品特性

    This is a rabbit polyclonal antibody against SOD1. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human SOD1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 154 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Hays, Naini, He, Mitsumoto, Rowland: "Sporadic amyotrophic lateral sclerosis and breast cancer: Hyaline conglomerate inclusions lead to identification of SOD1 mutation." in: Journal of the neurological sciences, Vol. 242, Issue 1-2, pp. 67-9, (2006) (PubMed).

  • 抗原

    SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

    别名

    SOD1

    背景

    SOD1 binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in its gene have been implicated as causes of familial amyotrophic lateral sclerosis.The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.
    Alias Symbols: ALS, ALS1, IPOA, SOD, homodimer, hSod1
    Protein Interaction Partner: SOD1, CRYAB, UBC, SMAD2, HDAC6, GSH1, OPTN, PRDX5, AHCYL1, TIAL1, PRDX2, SPTBN1, SOD2, PPP2CA, PPIA, PLS3, PRDX1, NME2, NME1, Hspa4l, Hspa4, Hspa2, Hspa1b, Hsph1, Dnaja1, Hspa8, Hspa5, Ccs, UBE3A, COMMD1, Stub1, SUMO4, DYNLT1, AMFR, MARCH5, RNF19A, PSMD4,
    Protein Size: 154

    分子量

    16 kDa

    基因ID

    6647

    NCBI登录号

    NM_000454, NP_000445

    UniProt

    P00441

    途径

    Sensory Perception of Sound, Transition Metal Ion Homeostasis
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