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SBDS 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects SBDS in WB 和 IHC. It exhibits reactivity toward 人, 小鼠, 大鼠, 犬, 马, 斑马鱼, Cow, 豚鼠 和 兔.It has been mentioned in 1 publication
产品编号 ABIN2782336
发货至: 中国
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Quick Overview for SBDS 抗体 (N-Term) (ABIN2782336)

抗原

See all SBDS 抗体
SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

适用

  • 37
  • 15
  • 15
  • 6
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
人, 小鼠, 大鼠, 犬, 马, 斑马鱼, Cow, 豚鼠, 兔

宿主

  • 34
  • 3

克隆类型

  • 30
  • 7
多克隆

标记

  • 20
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This SBDS antibody is un-conjugated

应用范围

  • 19
  • 9
  • 9
  • 7
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    N-Term

    序列

    LQTHSVFVNV SKGQVAKKED LISAFGTDDQ TEICKQILTK GEVQVSDKER

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 85%

    产品特性

    This is a rabbit polyclonal antibody against SBDS. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human SBDS
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 250 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Sezgin, Henson, Nihrane, Singh, Wattenberg, Alard, Ellis, Liu: "Impaired growth, hematopoietic colony formation, and ribosome maturation in human cells depleted of Shwachman-Diamond syndrome protein SBDS." in: Pediatric blood & cancer, Vol. 60, Issue 2, pp. 281-6, (2012) (PubMed).

  • 抗原

    SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

    别名

    SBDS

    背景

    SBDS is a member of a highly conserved protein family that exists from archaea to vertebrates and plants. The protein may function in RNA metabolism. Mutations within its gene are associated with Shwachman-Bodian-Diamond syndrome.This gene encodes a member of a highly conserved protein family that exists from archaea to vertebrates and plants. The encoded protein may function in RNA metabolism. Mutations within this gene are associated with Shwachman-Bodian-Diamond syndrome. An alternative transcript has been described, but its biological nature has not been determined. This gene has a closely linked pseudogene that is distally located.
    Alias Symbols: CGI-97, FLJ10917, SDS, SWDS
    Protein Interaction Partner: SUMO2, TYMS, PNP, IDH1, GOT1, UBC, CHAMP1, MPLKIP, MRPL53, SARNP, SLIRP, SRPRB, ACOT13, SRRM2, TIMM44, TOMM40, UBE4B, SCO2, SNX3, STX7, SF1, VDAC3, TIAL1, SPR, RBMS1, NDUFA7, NDUFA2, IDH3G, STOM, ACAA1, ACD, TERF2IP, POT1, TERF1, CLN3,
    Protein Size: 250

    分子量

    28 kDa

    基因ID

    51119

    NCBI登录号

    NM_016038, NP_057122

    UniProt

    Q9Y3A5

    途径

    Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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