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GLUD1 抗体 (N-Term)

Name: GLUD1 抗体 (N-Term)
SKU: ABIN2782330
Availability: OutOfStock

This anti-GLUD1 antibody is a 兔多克隆 antibody detecting GLUD1 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 马, Pig, 斑马鱼, 犬, 兔, 绵羊和豚鼠. This Primary Antibody has been cited in 2+ publications.

Host: Rabbit Target Name: SERPINA3 Sample Type: Human Adult Placenta Antibody Dilution: 1. (GLUD1 抗体 (N-Term))

Host: Rabbit Target Name: GNAS Sample Type: Human Fetal Heart Antibody Dilution: 1. (GLUD1 抗体 (N-Term))

Image no. 3 for anti-Glutamate Dehydrogenase 1 (GLUD1) (N-Term) antibody (ABIN2782330) (GLUD1 抗体 (N-Term))

Immunohistochemistry (IHC) image for anti-Glutamate Dehydrogenase 1 (GLUD1) (N-Term) antibody (ABIN2782330) (GLUD1 抗体 (N-Term))

IHC

Host: Rabbit Target Name: NOP56 Sample Type: Human Fetal Brain Antibody Dilution: 1. (GLUD1 抗体 (N-Term))

lanes 5: rat kidney cordex lanes 6: rat kidney proximal tubules prepped from cortex lanes 7: LLCPK-F+ pig kidney proximal tubule tissue culture lysate lanes 8: rat brain supernatant (GLUD1 抗体 (N-Term))

Host: Rabbit Target Name: HIRIP3 Sample Type: 293T Antibody Dilution: 1. (GLUD1 抗体 (N-Term))

Host: Rabbit Target Name: GLUD1 Sample Tissue: Rat Skeletal Muscle Antibody Dilution: 1ug/ml (GLUD1 抗体 (N-Term))

Host: Rabbit Target Name: GLUD1 Sample Type: Human Fetal Liver Lane A: Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration: 1ug/ml Peptide Concentration: 5ug/ml Lysate Quantity: 25ug/lane/lane Gel Concentration: 0. (GLUD1 抗体 (N-Term))

GLUD1 antibody - N-terminal region validated by WB using Fetal Liver Lysate at 1ug/ml. (GLUD1 抗体 (N-Term))

Immunohistochemistry with pFA fixed human pancreas tissue tissue (GLUD1 抗体 (N-Term))

IHC

Immunohistochemistry with CORTEX/KIDNEY tissue (GLUD1 抗体 (N-Term))

IHC

Host: Rabbit Target Name: GLUD1 Sample Tissue: Human Fetal Liver Antibody Dilution: 1. (GLUD1 抗体 (N-Term))

13 images

(2 references)

产品编号 ABIN2782330

发货至: 中国

Quick Overview for GLUD1 抗体 (N-Term) (ABIN2782330)

抗原

See all GLUD1 抗体

GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))

适用

人, 小鼠, 大鼠, Cow, 马, Pig, 斑马鱼, 犬, 兔, 绵羊, 豚鼠

宿主

兔

克隆类型

多克隆

标记

This GLUD1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product GLUD1 Primary Antibody

抗原表位
6

3

3

2

1

1

1

1

1
N-Term

序列

AKAGVKINPK NYTDNELEKI TRRFTMELAK KGFIGPGIDV PAPDMSTGER

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

产品特性

This is a rabbit polyclonal antibody against GLUD1. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human GLUD1
anti-Glutamate Dehydrogenase 1 (GLUD1) antibody
GLUD1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Glutamate Dehydrogenase 1 (GLUD1) (AA 54-240) antibody
GLUD1 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-Glutamate Dehydrogenase 1 (GLUD1) antibody
GLUD1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated

anti-Glutamate Dehydrogenase 1 (GLUD1) (AA 65-273) antibody
GLUD1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Glutamate Dehydrogenase 1 (GLUD1) (N-Term) antibody
GLUD1 适用: 人, 小鼠, 大鼠, Cow, 马, Pig, 斑马鱼, 犬, 绵羊, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Glutamate Dehydrogenase 1 (GLUD1) (AA 182-231) antibody
GLUD1 适用: 人, 小鼠, 大鼠, Cow, 马, Pig, 斑马鱼, 兔, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Glutamate Dehydrogenase 1 (GLUD1) antibody
GLUD1 适用: 人 WB, ELISA, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Glutamate Dehydrogenase 1 (GLUD1) (AA 93-107) antibody
GLUD1 适用: 人, 小鼠, 马, Pig, 猴 WB, IHC, ELISA, IHC (p) 宿主: 山羊 Polyclonal unconjugated

anti-Glutamate Dehydrogenase 1 (GLUD1) (N-Term) antibody
GLUD1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated

anti-Glutamate Dehydrogenase 1 (GLUD1) (N-Term) antibody
GLUD1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 558 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Spanaki, Kotzamani, Plaitakis: "Widening Spectrum of Cellular and Subcellular Expression of Human GLUD1 and GLUD2 Glutamate Dehydrogenases Suggests Novel Functions." in: Neurochemical research, Vol. 42, Issue 1, pp. 92-107, (2016) (PubMed).

Spanaki, Kotzamani, Petraki, Drakos, Plaitakis: "Expression of human GLUD1 and GLUD2 glutamate dehydrogenases in steroid producing tissues." in: Molecular and cellular endocrinology, Vol. 415, pp. 1-11, (2015) (PubMed).
抗原

GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))

别名

GLUD1

背景

L-glutamate dehydrogenase (EC 1.4.1.3) has a central role in nitrogen metabolism in plants and animals. Glutamate dehydrogenase is found in all organisms and catalyzes the oxidative deamination of 1-glutamate to 2-oxoglutarate. Glutamate, the main substrate of GLUD, is present in brain in concentrations higher than in other organs. In nervous tissue, GLUD appears to function in both the synthesis and the catabolism of glutamate and perhaps in ammonia detoxification.L-glutamate dehydrogenase (EC 1.4.1.3) has a central role in nitrogen metabolism in plants and animals. Glutamate dehydrogenase is found in all organisms and catalyzes the oxidative deamination of 1-glutamate to 2-oxoglutarate (Smith et al., 2001 [PubMed 11254391]). Glutamate, the main substrate of GLUD, is present in brain in concentrations higher than in other organs. In nervous tissue, GLUD appears to function in both the synthesis and the catabolism of glutamate and perhaps in ammonia detoxification (Mavrothalassitis et al., 1988 [PubMed 3368458]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-51 M20867.1 1-51 52-3120 BC112946.1 16-3084
Alias Symbols: GDH, GDH1, GLUD, MGC132003
Protein Interaction Partner: FUS, UBC, DCP2, KLHL29, SUMO1, NEDD8, LSM1, ILK, CDK5, VTN, SEC62, STAT5A, ORM1, HPX, NR4A1, FN1, CRP, ASGR2, CUL3, ELAVL1, EBNA-LP, HDAC5, ICT1, GLUD1, DYNLL1, GOT2,
Protein Size: 558

分子量

56 kDa

基因ID

2746

NCBI登录号

NM_005271, NP_005262

UniProt

Q5TDP6

途径

Positive Regulation of Peptide Hormone Secretion, Warburg Effect