KNG1 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for KNG1 抗体 (C-Term) (ABIN2782315)
抗原
See all KNG1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
原理
- KNG1 Antibody - C-terminal region
-
序列
- ISLMKRPPGF SPFRSSRIGE IKEETTSHLR SCEYKGRPPK AGAEPASERE
-
预测反应
- Human: 100%
-
产品特性
- This is a rabbit polyclonal antibody against KNG1. It was validated on Western Blot.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of human KNG1
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45681-100UG
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- KNG1 (Kininogen 1 (KNG1))
-
别名
- KNG1
-
背景
-
Background Information: This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.
Gene Name: kininogen 1
Alternative Symbols: BK, BDK, KNG, HMWK
Protein Name: kininogen-1
-
分子量
- 32kDa
-
基因ID
- 3827
-
NCBI登录号
- NP_000884
-
UniProt
- P01042
-
途径
- ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process
抗原
-