KNG1 抗体 (Middle Region)
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北京 101111
Quick Overview for KNG1 抗体 (Middle Region) (ABIN2782314)
抗原
See all KNG1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- KNG1 Antibody - middle region
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序列
- YPGKDFVQPP TKICVGCPRD IPTNSPELEE TLTHTITKLN AENNATFYFK
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预测反应
- Horse: 85%, Human: 100%, Mouse: 77%, Pig: 92%
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产品特性
- This is a rabbit polyclonal antibody against KNG1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human KNG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8103996
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).
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- KNG1 (Kininogen 1 (KNG1))
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别名
- KNG1
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背景
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Background Information: Kininogens are inhibitors of thiol proteases. HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII and inhibits the thrombin- and plasmin-induced aggregation of thrombocytes. The active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects such as influence in smooth muscle contraction, induction of hypotension, natriuresis and diuresis, etc.
Gene Name: Kininogen 1
Alternative Symbols: BK, BDK, KNG, HMWK
Protein Name: Kininogen-1
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分子量
- 72kDa
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基因ID
- 3827
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NCBI登录号
- NP_001095886
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UniProt
- P01042
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途径
- ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process
抗原
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