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KNG1 抗体 (Middle Region)

There is 1 publication for this product available. The 兔 多克隆 anti-KNG1 antibody is suitable to detect KNG1 in samples from 人, 小鼠, Pig 和 马. It has been validated for WB.
产品编号 ABIN2782314
发货至: 中国
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Quick Overview for KNG1 抗体 (Middle Region) (ABIN2782314)

抗原

See all KNG1 抗体
KNG1 (Kininogen 1 (KNG1))

适用

  • 70
  • 11
  • 8
  • 3
  • 1
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  • 1
  • 1
人, 小鼠, Pig, 马

宿主

  • 73
  • 8
  • 4

克隆类型

  • 70
  • 15
多克隆

标记

  • 53
  • 6
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  • 2
  • 2
  • 2
  • 2
  • 2
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  • 1
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This KNG1 antibody is un-conjugated

应用范围

  • 63
  • 42
  • 34
  • 21
  • 11
  • 8
  • 8
  • 6
  • 4
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    YPGKDFVQPP TKICVGCPRD IPTNSPELEE TLTHTITKLN AENNATFYFK

    预测反应

    Horse: 85%, Human: 100%, Mouse: 77%, Pig: 92%

    产品特性

    This is a rabbit polyclonal antibody against KNG1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human KNG1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 644 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

  • 抗原

    KNG1 (Kininogen 1 (KNG1))

    别名

    KNG1

    背景

    Kininogens are inhibitors of thiol proteases. HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII and inhibits the thrombin- and plasmin-induced aggregation of thrombocytes. The active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects such as influence in smooth muscle contraction, induction of hypotension, natriuresis and diuresis, etc.
    Alias Symbols: BDK, KNG
    Protein Interaction Partner: Ance, ECE1, COPS6, RXFP4, CPN1, F11, HABP2, CTSK, PREP, MEP1A, ITGB2, GP1BA, KLKB1, KNG1, VTN, THBS1, F2, PLAUR, PLG, KLK1, KRT1, FTL, ELANE, CD93, CTSL, CTSS, CTSG, CAPN2, CAPN1, AGT, APP,
    Protein Size: 644

    分子量

    72 kDa

    基因ID

    3827

    NCBI登录号

    NM_001102416, NP_001095886

    UniProt

    P01042

    途径

    ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process
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