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RORA 抗体 (Middle Region)

This anti-RORA antibody (ABIN2782273) is a Rabbit Polyclonal antibody detecting RORA in WB, IHC. Suitable for Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig, Goat, Zebrafish (Danio rerio), Sheep.
产品编号 ABIN2782273
发货至: 中国

Quick Overview for RORA 抗体 (Middle Region) (ABIN2782273)

抗原

See all RORA 抗体
RORA (RAR-Related Orphan Receptor A (RORA))

适用

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人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 山羊, 斑马鱼, 绵羊

宿主

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  • 5

克隆类型

  • 69
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多克隆

标记

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This RORA antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    Middle Region

    序列

    GHTPEGSKAD SAVSSFYLDI QPSPDQSGLD INGIKPEPIC DYTPASGFFP

    预测反应

    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against RORA. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human RORA
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 556 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    RORA (RAR-Related Orphan Receptor A (RORA))

    别名

    RORA

    背景

    The protein encoded by RORA is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene.The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene.
    Alias Symbols: MGC119326, MGC119329, NR1F1, ROR1, ROR2, ROR3, RZRA, RZR-ALPHA
    Protein Interaction Partner: GFAP, NSD1, NCOA1, PSMC5, SMARCD3, PTBP1, VPRBP, UBC, EZH2, DDB1, LMO3, NR0B1, ZXDC, PNRC2, COPS5, PNRC1, EIF3I, PROX1, LRIF1, RUVBL1, CEBPB, NCOA2, MED1, EP300, RORA, MYOD1, NME2, NME1,
    Protein Size: 556

    分子量

    63 kDa

    基因ID

    6095

    NCBI登录号

    NM_134260, NP_599022

    UniProt

    P35398

    途径

    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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