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HNF4A 抗体 (Middle Region)

The 兔 多克隆 anti-HNF4A antibody (ABIN2782264) specifically detects HNF4A in WB. The antibody is reactive with 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 绵羊 和 斑马鱼 samples.
产品编号 ABIN2782264
发货至: 中国
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Quick Overview for HNF4A 抗体 (Middle Region) (ABIN2782264)

抗原

See all HNF4A 抗体
HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

适用

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人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 绵羊, 斑马鱼

宿主

  • 133
  • 10
  • 2

克隆类型

  • 91
  • 54
多克隆

标记

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This HNF4A antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    LPFQELQIDD NEYAYLKAII FFDPDAKGLS DPGKIKRLRS QVQVSLEDYI

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

    产品特性

    This is a rabbit polyclonal antibody against HNF4A. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human HNF4A
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 442 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

    别名

    HNF4A

    背景

    The protein encoded by HNF4A is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants.
    Alias Symbols: FLJ39654, HNF4, HNF4a7, HNF4a8, HNF4a9, MODY, MODY1, NR2A1, NR2A21, TCF, TCF14, HNF4alpha
    Protein Interaction Partner: PIAS4, SUMO1, SUMO2, RNF4, SUB1, CREBBP, TBP, TAF9, TAF6, TADA2A, GTF2H1, GTF2B, ANP32B, MDM2, GPS2, PPARGC1A, HNF4A, NCOA6, SMAD4, SMAD3, PNRC2, COPS5, PNRC1, NR0B2, NRIP1, UBE2I, PROX1, NPPA, SREBF2, VDR, MAPK3, MAPK1, SIRT1, SREBF1, XPO1, SP1, HDAC3, T
    Protein Size: 442

    分子量

    49 kDa

    基因ID

    3172

    NCBI登录号

    NM_001030003, NP_001025174

    UniProt

    P41235

    途径

    AMPK Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process
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