ZP2 抗体 (C-Term)
Quick Overview for ZP2 抗体 (C-Term) (ABIN2782230)
抗原
See all ZP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- PDSFPQWNVV VDGCAYDLDN YQTTFHPVGS SVTHPDHYQR FDMKAFAFVS
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预测反应
- Cow: 79%, Dog: 86%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Rabbit: 93%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against ZP2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human ZP2
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anti-Zona Pellucida Glycoprotein 2 (ZP2) antibody
ZP2 适用: 人, 大鼠, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Zona Pellucida Glycoprotein 2 (ZP2) (AA 651-745) antibodyZP2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Zona Pellucida Glycoprotein 2 (ZP2) (AA 353-616) antibodyZP2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Zona Pellucida Glycoprotein 2 (ZP2) (AA 651-745) antibodyZP2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Zona Pellucida Glycoprotein 2 (ZP2) (AA 440-716) antibodyZP2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Zona Pellucida Glycoprotein 2 (ZP2) (AA 400-509) antibodyZP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B9 unconjugated
anti-Zona Pellucida Glycoprotein 2 (ZP2) (AA 1-313) antibodyZP2 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Zona Pellucida Glycoprotein 2 (ZP2) (AA 511-544), (N-Term) antibodyZP2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zona Pellucida Glycoprotein 2 (ZP2) (AA 553-602) antibodyZP2 适用: 人, 马, Cow, 犬, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Zona Pellucida Glycoprotein 2 (ZP2) antibodyZP2 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 745 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ZP2 (Zona Pellucida Glycoprotein 2 (ZP2))
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别名
- ZP2
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背景
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The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. ZP2 is a structural component of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies.The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies.
Alias Symbols: ZPA, Zp-2
Protein Interaction Partner: ZPBP, ACR,
Protein Size: 745 -
分子量
- 68 kDa
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基因ID
- 7783
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NCBI登录号
- NM_003460, NP_003451
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UniProt
- Q05996
抗原
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