PTPRR 抗体 (C-Term)
Quick Overview for PTPRR 抗体 (C-Term) (ABIN2782200)
抗原
See all PTPRR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- NYTIRNLVLK QGSHTQHVKH YWYTSWPDHK TPDSAQPLLQ LMLDVEEDRL
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against PTPRR. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human PTPRR
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anti-Protein tyrosine Phosphatase, Receptor Type, R (PTPRR) (AA 1-412) antibody
PTPRR 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, R (PTPRR) (AA 1-657) antibodyPTPRR 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, R (PTPRR) (AA 1-657) antibodyPTPRR 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, R (PTPRR) antibodyPTPRR 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, R (PTPRR) (AA 282-331) antibodyPTPRR 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, Bat, 小鸡, 猴, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, R (PTPRR) (AA 425-632) antibodyPTPRR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, R (PTPRR) (AA 107-156) antibodyPTPRR 适用: 人, 小鼠, 犬, Cow, 豚鼠, 兔, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, R (PTPRR) (AA 72-121) antibodyPTPRR 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, Bat, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, R (PTPRR) (AA 240-400) antibodyPTPRR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, R (PTPRR) (C-Term) antibodyPTPRR 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 412 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PTPRR (Protein tyrosine Phosphatase, Receptor Type, R (PTPRR))
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别名
- PTPRR
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背景
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PTPRR is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domains, and thus represents a receptor-type PTP.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domains, and thus represents a receptor-type PTP. The similar gene predominately expressed in mouse brain was found to associate with, and thus regulate the activity and cellular localization of MAP kinases. The rat counterpart of this gene was reported to be regulated by the nerve growth factor, which suggested the function of this gene in neuronal growth and differentiation. Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, and an RNA component, encoded by this gene, that serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Mutations in this gene cause autosomal dominant dyskeratosis congenita, and may also be associated with some cases of aplastic anemia.
Alias Symbols: DKFZp781C1038, EC-PTP, FLJ34328, MGC131968, MGC148170, PCPTP1, PTP-SL, PTPBR7, PTPRQ
Protein Interaction Partner: MAPK3, MAPK1, MAPK7, PRKACA,
Protein Size: 412 -
分子量
- 46 kDa
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基因ID
- 5801
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NCBI登录号
- NM_130846, NP_570897
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UniProt
- Q7Z2V8
抗原
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